Veronika Temml
Veronika Temml
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Discovery and resupply of pharmacologically active plant-derived natural products: A review
AG Atanasov, B Waltenberger, EM Pferschy-Wenzig, T Linder, ...
Biotechnology advances 33 (8), 1582-1614, 2015
Potent inhibition of human 5-lipoxygenase and microsomal prostaglandin E2 synthase-1 by the anti-carcinogenic and anti-inflammatory agent embelin
AM Schaible, H Traber, V Temml, SM Noha, R Filosa, A Peduto, ...
Biochemical pharmacology 86 (4), 476-486, 2013
Impact of wines and wine constituents on cyclooxygenase-1, cyclooxygenase-2, and 5-lipoxygenase catalytic activity
Z Kutil, V Temml, D Maghradze, M Pribylova, M Dvorakova, D Schuster, ...
Mediators of inflammation 2014, 2014
Endogenous metabolites of vitamin E limit inflammation by targeting 5-lipoxygenase
H Pein, A Ville, S Pace, V Temml, U Garscha, M Raasch, K Alsabil, ...
Nature communications 9 (1), 1-17, 2018
Anti-inflammatory activity of natural geranylated flavonoids: Cyclooxygenase and lipoxygenase inhibitory properties and proteomic analysis
Z Hanáková, J Hošek, Z Kutil, V Temml, P Landa, T Vaněk, D Schuster, ...
Journal of natural products 80 (4), 999-1006, 2017
Inhibition of 11β-hydroxysteroid dehydrogenase 2 by the fungicides itraconazole and posaconazole
KR Beck, M Bächler, A Vuorinen, S Wagner, M Akram, U Griesser, ...
Biochemical pharmacology 130, 93-103, 2017
Discovery of new liver X receptor agonists by pharmacophore modeling and shape-based virtual screening
V Temml, CV Voss, VM Dirsch, D Schuster
Journal of chemical information and modeling 54 (2), 367-371, 2014
Redox and non-redox mechanism of in vitro cyclooxygenase inhibition by natural quinones
P Landa, Z Kutil, V Temml, A Vuorinen, J Malik, M Dvorakova, P Marsik, ...
Planta medica 78 (04), 326-333, 2012
Pharmacophore modeling for COX-1 and-2 inhibitors with LigandScout in comparison to Discovery Studio
V Temml, T Kaserer, Z Kutil, P Landa, T Vanek, D Schuster
Future medicinal chemistry 6 (17), 1869-1881, 2014
Discovery of potent soluble epoxide hydrolase (sEH) inhibitors by pharmacophore-based virtual screening
B Waltenberger, U Garscha, V Temml, J Liers, O Werz, D Schuster, ...
Journal of chemical information and modeling 56 (4), 747-762, 2016
Pharmacological profile and efficiency in vivo of diflapolin, the first dual inhibitor of 5-lipoxygenase-activating protein and soluble epoxide hydrolase
U Garscha, E Romp, S Pace, A Rossi, V Temml, D Schuster, S König, ...
Scientific reports 7 (1), 1-14, 2017
Elucidation of the molecular mechanism and the efficacy in vivo of a novel 1,4‐benzoquinone that inhibits 5‐lipoxygenase
AM Schaible, R Filosa, V Temml, V Krauth, M Matteis, A Peduto, F Bruno, ...
British journal of pharmacology 171 (9), 2399-2412, 2014
Lignans from Carthamus tinctorius suppress tryptophan breakdown via indoleamine 2, 3-dioxygenase
S Kuehnl, S Schroecksnadel, V Temml, JM Gostner, H Schennach, ...
Phytomedicine 20 (13), 1190-1195, 2013
Discovery of the first dual inhibitor of the 5-lipoxygenase-activating protein and soluble epoxide hydrolase using pharmacophore-based virtual screening
V Temml, U Garscha, E Romp, G Schubert, J Gerstmeier, Z Kutil, ...
Scientific reports 7 (1), 1-8, 2017
The 5-lipoxygenase inhibitor RF-22c potently suppresses leukotriene biosynthesis in cellulo and blocks bronchoconstriction and inflammation in vivo
AM Schaible, R Filosa, V Krauth, V Temml, S Pace, U Garscha, S Liening, ...
Biochemical pharmacology 112, 60-71, 2016
Effect of Dietary Stilbenes on 5-Lipoxygenase and Cyclooxygenases Activities In Vitro
Z Kutil, M Kvasnicova, V Temml, D Schuster, P Marsik, EF Cusimamani, ...
International Journal of Food Properties 18 (7), 1471-1477, 2015
Inhibition of In Vitro Leukotriene B4 Biosynthesis in Human Neutrophil Granulocytes and Docking Studies of Natural Quinones
P Landa, Z Kutil, V Temml, J Malik, L Kokoska, U Widowitz, M Pribylova, ...
Natural product communications 8 (1), 1934578X1300800124, 2013
Optimization of benzoquinone and hydroquinone derivatives as potent inhibitors of human 5-lipoxygenase
A Peduto, M Scuotto, V Krauth, F Roviezzo, A Rossi, V Temml, V Esposito, ...
European journal of medicinal chemistry 127, 715-726, 2017
Semisynthetic and natural garcinoic acid isoforms as new mPGES-1 inhibitors
K Al Sabil, S Suor-Cherer, A Koeberle, G Viault, A Lavaud, V Temml, ...
Planta medica 82 (11/12), 1110-1116, 2016
Prospective performance evaluation of selected common virtual screening tools. Case study: Cyclooxygenase (COX) 1 and 2
T Kaserer, V Temml, Z Kutil, T Vanek, P Landa, D Schuster
European journal of medicinal chemistry 96, 445-457, 2015
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