Elodie Lafont

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Bruno SéguiProfessor of cell biologyAdresse e-mail validée de inserm.fr
Silvia SurinovaSenior Research Fellow - Team Lead in Proteomics, Head of the Proteomics Research TranslationalAdresse e-mail validée de ucl.ac.uk
Toshiro Okazaki石川県立大学　生物資源環境学部　客員教授Adresse e-mail validée de mbox.kyoto-inet.or.jp
Alexandra SevkoProkariumAdresse e-mail validée de prokarium.com
Eric ChevetInserm or Université Rennes 1Adresse e-mail validée de inserm.fr
Luigi MartinoWellcome TrustAdresse e-mail validée de wellcome.org
Andreas LinkermannMD - Clinician Scientist - HeisenbergprofessorAdresse e-mail validée de ukdd.de
Stephen HendersonCancer Institute, University College LondonAdresse e-mail validée de ucl.ac.uk
Anne von MaessenhausenMedizininische Klinik III, Nephrologie, Uniklinikum DresdenAdresse e-mail validée de ukdd.de
Katarzyna WojdylaPostdoc, Babraham InstituteAdresse e-mail validée de babraham.ac.uk
Sergio A. QuezadaUCL Cancer InstituteAdresse e-mail validée de ucl.ac.uk
Ankur ChakravarthyPostdoctoral Fellow, Princess Margaret Cancer CentreAdresse e-mail validée de ucl.ac.uk
Silvia von KarstedtJunior Research Group Leader, University of CologneAdresse e-mail validée de uni-koeln.de
Matthieu Le GalloInserm U1242 Chemistry Oncogenesis Stress Signaling, Rennes, FRANCEAdresse e-mail validée de univ-rennes1.fr
Tony AVRILINSERM OSS U1242 - PROSAC team - Centre Eugène Marquis - RennesAdresse e-mail validée de rennes.unicancer.fr
Klaus Schulze-OsthoffInterfaculty Institute of Biochemistry, University of TübingenAdresse e-mail validée de uni-tuebingen.de
Martin R SprickHI-STEM gGmbH, DKFZ-HeidelbergAdresse e-mail validée de dkfz.de
M SpitPostdoc LUMCAdresse e-mail validée de lumc.nl
Kazuyuki KitataniSetsunan UniversityAdresse e-mail validée de pharm.setsunan.ac.jp
Nieves PeltzerUniversity of CologneAdresse e-mail validée de uni-koeln.de

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Elodie Lafont

University of Rennes, INSERM U1242, Contact: elodie.lafont@inserm.fr

Adresse e-mail validée de inserm.fr

Death Receptors Ubiquitin Cell Death Proteostasis Cancer


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LUBAC-recruited CYLD and A20 regulate gene activation and cell death by exerting opposing effects on linear ubiquitin in signaling complexes P Draber, S Kupka, M Reichert, H Draberova, E Lafont, D de Miguel, ... Cell reports 13 (10), 2258-2272, 2015	289	2015
TBK1 and IKKε prevent TNF-induced cell death by RIPK1 phosphorylation E Lafont, P Draber, E Rieser, M Reichert, S Kupka, D de Miguel, ... Nature cell biology 20 (12), 1389-1399, 2018	224	2018
The TRAIL-induced cancer secretome promotes a tumor-supportive immune microenvironment via CCR2 T Hartwig, A Montinaro, S von Karstedt, A Sevko, S Surinova, ... Molecular cell 65 (4), 730-742. e5, 2017	211	2017
LUBAC is essential for embryogenesis by preventing cell death and enabling haematopoiesis N Peltzer, M Darding, A Montinaro, P Draber, H Draberova, S Kupka, ... Nature 557 (7703), 112-117, 2018	174	2018
The natural marine anhydrophytosphingosine, Jaspine B, induces apoptosis in melanoma cells by interfering with ceramide metabolism Y Salma, E Lafont, N Therville, S Carpentier, MJ Bonnafé, T Levade, ... Biochemical pharmacology 78 (5), 477-485, 2009	131	2009
The linear ubiquitin chain assembly complex regulates TRAIL‐induced gene activation and cell death E Lafont, C Kantari‐Mimoun, P Draber, D De Miguel, T Hartwig, ... The EMBO journal 36 (9), 1147-1166, 2017	125	2017
Caspase-mediated inhibition of sphingomyelin synthesis is involved in FasL-triggered cell death E Lafont, D Milhas, S Carpentier, V Garcia, ZX Jin, H Umehara, T Okazaki, ... Cell Death & Differentiation 17 (4), 642-654, 2010	68	2010
Paving TRAIL’s path with ubiquitin E Lafont, T Hartwig, H Walczak Trends in biochemical sciences 43 (1), 44-60, 2018	46	2018
The Linear ubiquitin chain assembly complex acts as a liver tumor suppressor and inhibits hepatocyte apoptosis and hepatitis Y Shimizu, N Peltzer, A Sevko, E Lafont, A Sarr, H Draberova, H Walczak Hepatology 65 (6), 1963-1978, 2017	34	2017
Caspase-10-dependent cell death in Fas/CD95 signalling is not abrogated by caspase inhibitor zVAD-fmk E Lafont, D Milhas, J Teissié, N Therville, N Andrieu-Abadie, T Levade, ... PloS one 5 (10), e13638, 2010	29	2010
Death sentence: the tale of a fallen endoplasmic reticulum EP McGrath, FG Centonze, E Chevet, T Avril, E Lafont Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1868 (6), 119001, 2021	28	2021
Targeting of T/Tn antigens with a plant lectin to kill human leukemia cells by photochemotherapy G Poiroux, M Pitie, R Culerrier, E Lafont, B Ségui, EJM Van Damme, ... PLoS One 6 (8), e23315, 2011	28	2011
Therapeutic approaches targeting CD95L/CD95 signaling in cancer and autoimmune diseases V Risso, E Lafont, M Le Gallo Cell Death & Disease 13 (3), 248, 2022	15	2022
Regulation of death and growth signals at the plasma membrane by sphingomyelin synthesis: implications for hematological malignancies E Lafont, K Kitatani, T Okazaki, B Segui Recent patents on anti-cancer drug discovery 6 (3), 324-333, 2011	15	2011
Ordering of ceramide formation and caspase-9 activation in CD95L-induced Jurkat leukemia T cell apoptosis E Lafont, R Dupont, N Andrieu-Abadie, T Okazaki, K Schulze-Osthoff, ... Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2012	13	2012
Stress management: death receptor signalling and cross-talks with the unfolded protein response in cancer E Lafont Cancers 12 (5), 1113, 2020	11	2020
UFMylation: a ubiquitin-like modification X Zhou, SJ Mahdizadeh, M Le Gallo, LA Eriksson, E Chevet, E Lafont Trends in Biochemical Sciences, 2024	3	2024
IRE1 endoribonuclease signaling promotes myeloid cell infiltration in glioblastoma J Obacz, J Archambeau, E Lafont, M Nivet, S Martin, M Aubry, ... Neuro-oncology 26 (5), 858-871, 2024	2	2024
Metalloprotease‐mediated cleavage of CD95 ligand V Risso, M Thomas, B Guével, R Lavigne, E Com, S Martin, M Nivet, ... The FEBS Journal 290 (12), 3145-3164, 2023	2	2023
A novel optinEuRin stress connection in glaucoma E Lafont, T Avril The FEBS Journal 290 (12), 3105-3109, 2023	1	2023

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