Suivre
Yu Leo Lei
Yu Leo Lei
Associate Professor (tenured), The University of Texas M.D. Anderson Cancer Center
Adresse e-mail validée de mdanderson.org
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Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1
DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ...
autophagy 17 (1), 1-382, 2021
13143*2021
Fatty acid–induced NLRP3-ASC inflammasome activation interferes with insulin signaling
H Wen, D Gris, Y Lei, S Jha, L Zhang, MTH Huang, WJ Brickey, JPY Ting
Nature immunology 12 (5), 408-415, 2011
18492011
NLRX1 is a regulator of mitochondrial antiviral immunity
CB Moore, DT Bergstralh, JA Duncan, Y Lei, TE Morrison, ...
Nature 451 (7178), 573-577, 2008
6642008
NLRX1 protein attenuates inflammatory responses to infection by interfering with the RIG-I-MAVS and TRAF6-NF-κB signaling pathways
IC Allen, CB Moore, M Schneider, Y Lei, BK Davis, MA Scull, D Gris, ...
Immunity 34 (6), 854-865, 2011
3972011
The intermucosal connection between the mouth and gut in commensal pathobiont-driven colitis
S Kitamoto, H Nagao-Kitamoto, Y Jiao, MG Gillilland, A Hayashi, J Imai, ...
Cell 182 (2), 447-462. e14, 2020
3872020
How the noninflammasome NLRs function in the innate immune system
JPY Ting, JA Duncan, Y Lei
Science 327 (5963), 286, 2010
3562010
Identification of the Cell-Intrinsic and -Extrinsic Pathways Downstream of EGFR and IFNγ That Induce PD-L1 Expression in Head and Neck Cancer
F Concha-Benavente, RM Srivastava, S Trivedi, Y Lei, U Chandran, ...
Cancer Research 76 (5), 1031-43, 2016
3272016
The mitochondrial proteins NLRX1 and TUFM form a complex that regulates type I interferon and autophagy
Y Lei, H Wen, Y Yu, DJ Taxman, L Zhang, DG Widman, KV Swanson, ...
Immunity 36 (6), 933-946, 2012
2922012
Amplifying STING activation by cyclic dinucleotide–manganese particles for local and systemic cancer metalloimmunotherapy
X Sun, Y Zhang, J Li, KS Park, K Han, X Zhou, Y Xu, J Nam, J Xu, X Shi, ...
Nature nanotechnology 16 (11), 1260-1270, 2021
2852021
PD-1/SHP-2 inhibits Tc1/Th1 phenotypic responses and the activation of T cells in the tumor microenvironment
J Li, HB Jie, Y Lei, N Gildener-Leapman, S Trivedi, T Green, LP Kane, ...
Cancer research 75 (3), 508-518, 2015
2392015
MAVS-mediated apoptosis and its inhibition by viral proteins
Y Lei, CB Moore, RM Liesman, BP O'Connor, DT Bergstralh, ZJ Chen, ...
PloS one 4 (5), e5466, 2009
2322009
PD-1 Status in CD8+ T Cells Associates with Survival and Anti-PD-1 Therapeutic Outcomes in Head and Neck Cancer
BA Kansy, F Concha-Benavente, RM Srivastava, HB Jie, G Shayan, Y Lei, ...
Cancer research 77 (22), 6353-6364, 2017
1972017
STINGel: Controlled release of a cyclic dinucleotide for enhanced cancer immunotherapy
DG Leach, N Dharmaraj, SL Piotrowski, TL Lopez-Silva, YL Lei, ...
Biomaterials 163, 67-75, 2018
1822018
Inhibition of ATM increases interferon signaling and sensitizes pancreatic cancer to immune checkpoint blockade therapy
Q Zhang, MD Green, X Lang, J Lazarus, JD Parsels, S Wei, LA Parsels, ...
Cancer research 79 (15), 3940-3951, 2019
1732019
Ovarian cancer stem cells and macrophages reciprocally interact through the WNT pathway to promote pro-tumoral and malignant phenotypes in 3D engineered microenvironments
S Raghavan, P Mehta, Y Xie, YL Lei, G Mehta
Journal for immunotherapy of cancer 7, 1-15, 2019
1722019
Phase I dendritic cell p53 peptide vaccine for head and neck cancer
PJ Schuler, M Harasymczuk, C Visus, A DeLeo, S Trivedi, Y Lei, A Argiris, ...
Clinical Cancer Research 20 (9), 2433-2444, 2014
1712014
O-GlcNAc transferase suppresses inflammation and necroptosis by targeting receptor-interacting serine/threonine-protein kinase 3
X Li, W Gong, H Wang, T Li, KS Attri, RE Lewis, AC Kalil, F Bhinderwala, ...
Immunity 50 (3), 576-590. e6, 2019
1432019
O-GlcNAc transferase suppresses inflammation and necroptosis by targeting receptor-interacting serine/threonine-protein kinase 3
X Li, W Gong, H Wang, T Li, KS Attri, RE Lewis, AC Kalil, F Bhinderwala, ...
Immunity 50 (3), 576-590. e6, 2019
1432019
Mitigating SOX2-potentiated immune escape of head and neck squamous cell carcinoma with a STING-inducing nanosatellite vaccine
YS Tan, K Sansanaphongpricha, Y Xie, CR Donnelly, X Luo, BR Heath, ...
Clinical Cancer Research 24 (17), 4242-4255, 2018
1302018
Plexin-A4–semaphorin 3A signaling is required for Toll-like receptor–and sepsis-induced cytokine storm
H Wen, Y Lei, SY Eun, J P.-Y. Ting
Journal of Experimental Medicine 207 (13), 2943-2957, 2010
1262010
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