Pseudouridine profiling reveals regulated mRNA pseudouridylation in yeast and human cells TM Carlile, MF Rojas-Duran, B Zinshteyn, H Shin, KM Bartoli, WV Gilbert Nature 515 (7525), 143-146, 2014 | 930 | 2014 |
Meiosis I is established through division-specific translational control of a cyclin TM Carlile, A Amon Cell 133 (2), 280-291, 2008 | 241 | 2008 |
Loss-of-function mutations in the RNA biogenesis factor NAF1 predispose to pulmonary fibrosis–emphysema SE Stanley, DL Gable, CL Wagner, TM Carlile, VS Hanumanthu, ... Science Translational Medicine 8 (351), 351ra107-351ra107, 2016 | 203 | 2016 |
Regulated Formation of an Amyloid-like Translational Repressor Governs Gametogenesis LE Berchowitz, G Kabachinski, MR Walker, TM Carlile, WV Gilbert, ... Cell 163 (2), 406-418, 2015 | 172 | 2015 |
mRNA structure determines modification by pseudouridine synthase 1 TM Carlile, NM Martinez, C Schaening, A Su, TA Bell, B Zinshteyn, ... Nature chemical biology 15 (10), 966-974, 2019 | 109 | 2019 |
Burkholderia cenocepacia phage BcepMu and a family of Mu-like phages encoding potential pathogenesis factors EJ Summer, CF Gonzalez, T Carlisle, LM Mebane, AM Cass, CG Savva, ... Journal of molecular biology 340 (1), 49-65, 2004 | 105 | 2004 |
Aneuploid yeast strains exhibit defects in cell growth and passage through START RR Thorburn, C Gonzalez, GA Brar, S Christen, TM Carlile, NT Ingolia, ... Molecular biology of the cell 24 (9), 1274-1289, 2013 | 102 | 2013 |
Human SNORA31 variations impair cortical neuron-intrinsic immunity to HSV-1 and underlie herpes simplex encephalitis FG Lafaille, O Harschnitz, YS Lee, P Zhang, ML Hasek, G Kerner, Y Itan, ... Nature Medicine 25 (12), 1873-1884, 2019 | 99 | 2019 |
Divergence and Mosaicism among Virulent Soil Phages of the Burkholderia cepacia Complex EJ Summer, CF Gonzalez, M Bomer, T Carlile, A Embry, AM Kucherka, ... Journal of Bacteriology 188 (1), 255-268, 2006 | 75 | 2006 |
Pseudo-Seq: genome-wide detection of pseudouridine modifications in RNA TM Carlile, MF Rojas-Duran, WV Gilbert Methods in enzymology 560, 219-245, 2015 | 59 | 2015 |
Genomes and characterization of phages Bcep22 and BcepIL02, founders of a novel phage type in Burkholderia cenocepacia JJ Gill, EJ Summer, WK Russell, SM Cologna, TM Carlile, AC Fuller, ... Journal of bacteriology 193 (19), 5300-5313, 2011 | 54 | 2011 |
Organotypic brain slice culture microglia exhibit molecular similarity to acutely-isolated adult microglia and provide a platform to study neuroinflammation ARD Delbridge, D Huh, M Brickelmaier, JC Burns, C Roberts, R Challa, ... Frontiers in cellular neuroscience 14, 592005, 2020 | 42 | 2020 |
MOG autoantibodies trigger a tightly-controlled FcR and BTK-driven microglia proliferative response K Pellerin, SJ Rubino, JC Burns, BA Smith, CA McCarl, J Zhu, L Jandreski, ... Brain 144 (8), 2361-2374, 2021 | 34 | 2021 |
Conserved Methyltransferase Spb1 Targets mRNAs for Regulated Modification with 2′-O-Methyl Ribose KM Bartoli, C Schaening, T Carlile, WV Gilbert bioRxiv, 271916, 2018 | 24 | 2018 |
Transcriptome‐Wide Identification of Pseudouridine Modifications Using Pseudo‐seq TM Carlile, MF Rojas‐Duran, WV Gilbert Current protocols in molecular biology 112 (1), 4.25. 1-4.25. 24, 2015 | 22 | 2015 |
Next‐generation Bruton's tyrosine kinase inhibitor BIIB091 selectively and potently inhibits B cell and Fc receptor signaling and downstream functions in B cells and myeloid cells E Bame, H Tang, JC Burns, M Arefayene, K Michelsen, B Ma, I Marx, ... Clinical & translational immunology 10 (6), e1295, 2021 | 19 | 2021 |
In vivo genome editing using novel AAV-PHP variants rescues motor function deficits and extends survival in a SOD1-ALS mouse model YA Chen, MW Kankel, S Hana, SK Lau, MI Zavodszky, O McKissick, ... Gene Therapy 30 (5), 443-454, 2023 | 7 | 2023 |
SCD Inhibition Protects from α-Synuclein-Induced Neurotoxicity But Is Toxic to Early Neuron Cultures JW Nicholatos, J Groot, S Dhokai, D Tran, L Hrdlicka, TM Carlile, ... Eneuro 8 (4), 2021 | 5 | 2021 |
Benchmarking and optimization of a high‐throughput sequencing based method for transgene sequence variant analysis in biotherapeutic cell line development J Groot, Y Zhou, E Marshall, P Cullen, T Carlile, D Lin, CF Xu, J Crisafulli, ... Biotechnology Journal 16 (8), 2000548, 2021 | 2 | 2021 |
Efficacy and safety of a SOD1-targeting artificial miRNA delivered by AAV9 in mice are impacted by miRNA scaffold selection SK Chen, ZCE Hawley, MI Zavodszky, S Hana, D Ferretti, B Grubor, ... Molecular Therapy-Nucleic Acids 34, 2023 | 1 | 2023 |