| Covalent and allosteric inhibitors of the ATPase VCP/p97 induce cancer cell death P Magnaghi, R D'alessio, B Valsasina, N Avanzi, S Rizzi, D Asa, ... Nature chemical biology 9 (9), 548-556, 2013 | 381 | 2013 |
| Identification of N, 1, 4, 4-Tetramethyl-8-{[4-(4-methylpiperazin-1-yl) phenyl] amino}-4, 5-dihydro-1 H-pyrazolo [4, 3-h] quinazoline-3-carboxamide (PHA-848125), a Potent … MG Brasca, N Amboldi, D Ballinari, A Cameron, E Casale, G Cervi, ... Journal of medicinal chemistry 52 (16), 5152-5163, 2009 | 309* | 2009 |
| Thieno [3, 2-c] pyrazoles: A novel class of Aurora inhibitors with favorable antitumor activity S Bindi, D Fancelli, C Alli, D Berta, JA Bertrand, AD Cameron, P Cappella, ... Bioorganic & medicinal chemistry 18 (19), 7113-7120, 2010 | 39 | 2010 |
| Bicyclic carbohydrate-derived scaffolds for combinatorial libraries G Cervi, F Peri, C Battistini, C Gennari, F Nicotra Bioorganic & medicinal chemistry 14 (10), 3349-3367, 2006 | 37 | 2006 |
| Discovery and optimization of pyrrolo [1, 2-a] pyrazinones leads to novel and selective inhibitors of PIM kinases F Casuscelli, E Ardini, N Avanzi, E Casale, G Cervi, M D’Anello, D Donati, ... Bioorganic & medicinal chemistry 21 (23), 7364-7380, 2013 | 36 | 2013 |
| Use of multicomponent, domino, and other one-pot syntheses on solid phase: powerful tools for the generation of libraries of diverse and complex compounds M Pulici, G Cervi, K Martina, F Quartieri Combinatorial Chemistry & High Throughput Screening 6 (7), 693-727, 2003 | 34 | 2003 |
| 3, 4-diarylpyrazoles as protein kinase inhibitors M Pulici, F Zuccotto, A Badari, S Nuvoloni, G Cervi, G Traquandi, ... US Patent 8,541,575, 2013 | 31 | 2013 |
| Discovery of 2-(cyclohexylmethylamino) pyrimidines as a new class of reversible valosine containing protein inhibitors G Cervi, P Magnaghi, D Asa, N Avanzi, A Badari, D Borghi, M Caruso, ... Journal of medicinal chemistry 57 (24), 10443-10454, 2014 | 23 | 2014 |
| 3, 4-diarylpyrazoles as protein kinase inhibitors M Pulici, F Zuccotto, G Traquandi, S Biondaro, P Trifiro, A Badari, ... US Patent 8,946,250, 2015 | 20* | 2015 |
| 3, 4-dihydro-2H-pyrazino [1, 2-A] indol-1-one derivatives active as kinase inhibitors, process for their preparation and pharmaceutical compositions comprising them G Cervi, M D'anello, GME Papeo, B Salom US Patent 8,513,241, 2013 | 15 | 2013 |
| Isoquinolin-1 (2H)-one derivatives as PARP-1 inhibitors GME Papeo, JA Bertrand, G Cervi, B Forte, R Lupi, A Montagnoli, ... US Patent 8,592,416, 2013 | 8 | 2013 |
| Tetracyclic pyrazole derivatives as kinase inhibitors, process for their preparation and pharmaceutical compositions comprising them E Vanotti, G Cervi, M Pulici, M Menichincheri, M Varasi, P Vianello US Patent App. 10/545,768, 2006 | 8 | 2006 |
| Synthesis of a β-carboline scaffold properly functionalized for the generation of libraries of bioactive compounds B La Ferla, A Orsato, C Zona, G Cervi, G Papeo, ER Felder, F Nicotra Synthesis 2010 (04), 601-604, 2010 | 5 | 2010 |
| Pyrazolyl-pyrimidine derivatives as kinase inhibitors F Casuscelli, MG Brasca, M Caldarelli, G Cervi, T Disingrini, F Quartieri | 3 | 2012 |
| 3, 4-dihydro-2H-pyrrolo [1, 2-a] pyrazin-1-one derivatives for the modulation of the activity of protein kinases D Mirizzi, G Cervi, M D'anello, GME Papeo, R Ferguson, F Casuscelli US Patent 8,394,802, 2013 | 2 | 2013 |
| 3, 4-Dihydro-2H-pyrazino [1, 2-a] indol-1-one derivatives active as kinase inhibitors, process for their preparation and pharmaceutical compositions comprising them G Cervi, M D'anello, GME Papeo, B Salom US Patent 8,207,165, 2012 | 2 | 2012 |
| Isoquinolin-1 (2H)-one derivatives as PARP-1 inhibitors GME Papeo, JA Bertrand, G Cervi, B Forte, R Lupi, A Montagnoli, ... US Patent 8,993,594, 2015 | 1 | 2015 |
| Identification of potent VCP/p97/CDC48 inhibitors with distinct biochemical mechanisms including a reversible, allosteric inhibitor that activates the unfolded protein response … P Magnaghi, R D'Alessio, B Valsasina, NR Avanzi, S Rizzi, D Asa, ... Cancer Research 72 (8_Supplement), 2940-2940, 2012 | 1 | 2012 |
| Discovery and optimization of 4-pyrazolyl-2-aminopyrimidine derivatives as potent spleen tyrosine kinase (SYK) inhibitors G Cervi, R D'Alessio, S Bindi, L Buffa, A Burocchi, G Canevari, ... European Journal of Medicinal Chemistry, 116375, 2024 | | 2024 |
| NMS-0963 is a novel potent, selective and orally available Syk inhibitor with promising preclinical activity in diffuse large B-cell lymphoma G Saturno, M Modugno, P Orsini, G Cervi, L Buffa, I Motto, N Avanzi, ... Cancer Research 83 (7_Supplement), 4036-4036, 2023 | | 2023 |
