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Shawn B Egri
Shawn B Egri
Adresse e-mail validée de umassmed.edu
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Structural and functional analysis of the D614G SARS-CoV-2 spike protein variant
L Yurkovetskiy, X Wang, KE Pascal, C Tomkins-Tinch, TP Nyalile, Y Wang, ...
Cell 183 (3), 739-751. e8, 2020
10262020
KDM5 histone demethylase activity links cellular transcriptomic heterogeneity to therapeutic resistance
K Hinohara, HJ Wu, S Vigneau, TO McDonald, KJ Igarashi, KN Yamamoto, ...
Cancer cell 34 (6), 939-953. e9, 2018
1842018
Optimum exchange for calculation of excitation energies and hyperpolarizabilities of organic electro-optic chromophores
K Garrett, XA Sosa Vazquez, SB Egri, J Wilmer, LE Johnson, ...
Journal of Chemical Theory and Computation 10 (9), 3821-3831, 2014
1122014
SARS-CoV-2 Spike protein variant D614G increases infectivity and retains sensitivity to antibodies that target the receptor binding domain
L Yurkovetskiy, KE Pascal, C Tomkins-Tinch, T Nyalile, Y Wang, A Baum, ...
BioRxiv, 2020.07. 04.187757, 2020
822020
A library of phosphoproteomic and chromatin signatures for characterizing cellular responses to drug perturbations
L Litichevskiy, R Peckner, JG Abelin, JK Asiedu, AL Creech, JF Davis, ...
Cell systems 6 (4), 424-443. e7, 2018
762018
Study of mitotic chromatin supports a model of bookmarking by histone modifications and reveals nucleosome deposition patterns
E Javasky, I Shamir, S Gandhi, S Egri, O Sandler, SB Rothbart, N Kaplan, ...
Genome research 28 (10), 1455-1466, 2018
382018
KDM5 histone demethylase activity links cellular transcriptomic heterogeneity to therapeutic resistance
K Hinohara, HJ Wu, S Vigneau, TO McDonald, KJ Igarashi, KN Yamamoto, ...
Cancer cell 35 (2), 330-332, 2019
322019
JAK–STAT Signaling in Inflammatory Breast Cancer Enables Chemotherapy-Resistant Cell States
LE Stevens, G Peluffo, X Qiu, D Temko, A Fassl, Z Li, A Trinh, ...
Cancer research 83 (2), 264-284, 2023
272023
Cryo-EM structures of the human GATOR1-Rag-Ragulator complex reveal a spatial-constraint regulated GAP mechanism
SB Egri, C Ouch, HT Chou, Z Yu, K Song, C Xu, K Shen
Molecular cell 82 (10), 1836-1849. e5, 2022
232022
Protein interaction studies in human induced neurons indicate convergent biology underlying autism spectrum disorders
G Pintacuda, YHH Hsu, K Tsafou, KW Li, JM Martín, J Riseman, ...
Cell Genomics 3 (3), 2023
162023
Characterization of aminoacyl-tRNA synthetase stability and substrate interaction by differential scanning fluorimetry
JA Abbott, NM Livingston, SB Egri, E Guth, CS Francklyn
Methods 113, 64-71, 2017
152017
A phosphoproteomic signature in endothelial cells predicts vascular toxicity of tyrosine kinase inhibitors used in CML
S Gopal, Q Lu, JJ Man, W Baur, SP Rao, L Litichevskiy, M Papanastasiou, ...
Blood advances 2 (14), 1680-1684, 2018
132018
Termi-Luc: a versatile assay to monitor full-protein release from ribosomes
D Susorov, S Egri, AA Korostelev
RNA 26 (12), 2044-2050, 2020
122020
Proteomic profiling dataset of chemical perturbations in multiple biological backgrounds
DO Dele-Oni, KE Christianson, SB Egri, AS Vaca Jacome, KC DeRuff, ...
Scientific Data 8 (1), 226, 2021
92021
S: D614G and S: H655Y are gateway mutations that act epistatically to promote SARS-CoV-2 variant fitness
L Yurkovetskiy, S Egri, C Kurhade, MA Diaz-Salinas, JA Jaimes, T Nyalile, ...
bioRxiv, 2023
52023
Interaction studies of risk proteins in human induced neurons reveal convergent biology and novel mechanisms underlying autism spectrum disorders
G Pintacuda, YHH Hsu, K Tsafou, KW Li, JM Martín, J Riseman, ...
MedRxiv, 2021.10. 07.21264575, 2021
52021
Detergent modulates the conformational equilibrium of SARS-CoV-2 Spike during cryo-EM structural determination
SB Egri, X Wang, MA Díaz-Salinas, J Luban, NV Dudkina, JB Munro, ...
Nature Communications 14 (1), 2527, 2023
42023
Structural and functional analysis of the D614G SARS-CoV-2 spike protein variant
X Wang, L Yurkovetskiy, K Shen, J Luban, D Natalya, K Pascal, ...
Microscopy and Microanalysis 27 (S1), 3260-3262, 2021
32021
Structure of the Schizosaccharomyces pombe Gtr-Lam complex reveals evolutionary divergence of mTORC1-dependent amino acid sensing
SD Tettoni, SB Egri, DD Doxsey, K Veinotte, C Ouch, JY Chang, K Song, ...
Structure 31 (9), 1065-1076. e5, 2023
22023
Redundant electrostatic interactions between GATOR1 and the Rag GTPase heterodimer drive efficient amino acid sensing in human cells
DD Doxsey, SD Tettoni, SB Egri, K Shen
Journal of Biological Chemistry 299 (7), 2023
22023
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