Tuft-cell-derived IL-25 regulates an intestinal ILC2–epithelial response circuit J Von Moltke, M Ji, HE Liang, RM Locksley Nature 529 (7585), 221-225, 2016 | 1181 | 2016 |
Type 2 innate lymphoid cells control eosinophil homeostasis JC Nussbaum, SJ Van Dyken, J von Moltke, LE Cheng, A Mohapatra, ... Nature 502 (7470), 245, 2013 | 1093 | 2013 |
Differential requirement for Caspase-1 autoproteolysis in pathogen-induced cell death and cytokine processing P Broz, J von Moltke, JW Jones, RE Vance, DM Monack Cell host & microbe 8 (6), 471-483, 2010 | 701 | 2010 |
The N-ethyl-N-nitrosourea-induced Goldenticket mouse mutant reveals an essential function of Sting in the in vivo interferon response to Listeria monocytogenes and cyclic … JD Sauer, K Sotelo-Troha, J Von Moltke, KM Monroe, CS Rae, ... Infection and immunity 79 (2), 688-694, 2011 | 641 | 2011 |
Critical function for Naip5 in inflammasome activation by a conserved carboxy-terminal domain of flagellin KL Lightfield, J Persson, SW Brubaker, CE Witte, J Von Moltke, ... Nature immunology 9 (10), 1171-1178, 2008 | 558 | 2008 |
Rapid induction of inflammatory lipid mediators by the inflammasome in vivo J von Moltke, NJ Trinidad, M Moayeri, AF Kintzer, SB Wang, ... Nature 490 (7418), 107-111, 2012 | 488 | 2012 |
Recognition of bacteria by inflammasomes J von Moltke, JS Ayres, EM Kofoed, J Chavarría-Smith, RE Vance Annual review of immunology 31 (1), 73-106, 2013 | 472 | 2013 |
Detection of succinate by intestinal tuft cells triggers a type 2 innate immune circuit MS Nadjsombati, JW McGinty, MR Lyons-Cohen, JB Jaffe, L DiPeso, ... Immunity 49 (1), 33-41. e7, 2018 | 462 | 2018 |
A metabolite-triggered tuft cell-ILC2 circuit drives small intestinal remodeling C Schneider, CE O’Leary, J von Moltke, HE Liang, QY Ang, PJ Turnbaugh, ... Cell 174 (2), 271-284. e14, 2018 | 398 | 2018 |
NAIP-NLRC4 inflammasomes coordinate intestinal epithelial cell expulsion with eicosanoid and IL-18 release via activation of caspase-1 and-8 I Rauch, KA Deets, DX Ji, J von Moltke, JL Tenthorey, AY Lee, NH Philip, ... Immunity 46 (4), 649-659, 2017 | 390 | 2017 |
Thymic tuft cells promote an IL-4-enriched medulla and shape thymocyte development CN Miller, I Proekt, J von Moltke, KL Wells, AR Rajpurkar, H Wang, ... Nature 559 (7715), 627-631, 2018 | 261 | 2018 |
Differential activation of the transcription factor IRF1 underlies the distinct immune responses elicited by type I and type III interferons A Forero, S Ozarkar, H Li, CH Lee, EA Hemann, MS Nadjsombati, ... Immunity 51 (3), 451-464. e6, 2019 | 233 | 2019 |
Respiratory chain dysfunction and oxidative stress correlate with severity of primary CoQ10 deficiency CM Quinzii, LC López, J Von-Moltke, A Naini, S Krishna, M Schuelke, ... The FASEB journal: official publication of the Federation of American …, 2008 | 185 | 2008 |
Tuft-cell-derived leukotrienes drive rapid anti-helminth immunity in the small intestine but are dispensable for anti-protist immunity JW McGinty, HA Ting, TE Billipp, MS Nadjsombati, DM Khan, NA Barrett, ... Immunity 52 (3), 528-541. e7, 2020 | 171 | 2020 |
Leukotrienes provide an NFAT-dependent signal that synergizes with IL-33 to activate ILC2s J von Moltke, CE O’Leary, NA Barrett, Y Kanaoka, KF Austen, ... Journal of Experimental Medicine 214 (1), 27-37, 2017 | 166 | 2017 |
The cysteinyl leukotriene 3 receptor regulates expansion of IL-25–producing airway brush cells leading to type 2 inflammation LG Bankova, DF Dwyer, E Yoshimoto, S Ualiyeva, JW McGinty, H Raff, ... Science immunology 3 (28), eaat9453, 2018 | 144 | 2018 |
The immune function of tuft cells at gut mucosal surfaces and beyond HA Ting, J von Moltke The Journal of Immunology 202 (5), 1321-1329, 2019 | 123 | 2019 |
MicroRNA regulation of type 2 innate lymphoid cell homeostasis and function in allergic inflammation PB Singh, HH Pua, HC Happ, C Schneider, J von Moltke, RM Locksley, ... Journal of Experimental Medicine 214 (12), 3627-3643, 2017 | 95 | 2017 |
Interpreting heterogeneity in intestinal tuft cell structure and function A Banerjee, ET McKinley, J von Moltke, RJ Coffey, KS Lau The Journal of clinical investigation 128 (5), 1711-1719, 2018 | 85 | 2018 |
Epithelial STAT6 O-GlcNAcylation drives a concerted anti-helminth alarmin response dependent on tuft cell hyperplasia and Gasdermin C M Zhao, K Ren, X Xiong, Y Xin, Y Zou, JC Maynard, A Kim, AP Battist, ... Immunity 55 (4), 623-638. e5, 2022 | 69 | 2022 |