Michael D Toney
Michael D Toney
Professor of Chemistry, University of California, Davis
Adresse e-mail validée de ucdavis.edu - Page d'accueil
TitreCitée parAnnée
A simple method for site-directed mutagenesis using the polymerase chain reaction
A Hemsley, N Arnheim, MD Toney, G Cortopassi, DJ Galas
Nucleic acids research 17 (16), 6545-6551, 1989
6671989
Reaction specificity in pyridoxal phosphate enzymes
MD Toney
Archives of biochemistry and biophysics 433 (1), 279-287, 2005
2652005
Direct Bronsted analysis of the restoration of activity to a mutant enzyme by exogenous amines
MD Toney, JF Kirsch
Science 243 (4897), 1485-1488, 1989
2481989
Dialkylglycine decarboxylase structure: bifunctional active site and alkali metal sites
MD Toney, E Hohenester, SW Cowan, JN Jansonius
Science 261 (5122), 756-759, 1993
2201993
Serine racemase modulates intracellular D-serine levels through an α, β-elimination activity
VN Foltyn, I Bendikov, J De Miranda, R Panizzutti, E Dumin, M Shleper, ...
Journal of Biological Chemistry 280 (3), 1754-1763, 2005
1802005
Cloning and characterization of a phosphopantetheinyl transferase from Streptomyces verticillus ATCC15003, the producer of the hybrid peptide–polyketide antitumor drug bleomycin
C Sánchez, L Du, DJ Edwards, MD Toney, B Shen
Chemistry & biology 8 (7), 725-738, 2001
1802001
Evidence for a two-base mechanism involving tyrosine-265 from arginine-219 mutants of alanine racemase
S Sun, MD Toney
Biochemistry 38 (13), 4058-4065, 1999
1401999
A novel 4-methylideneimidazole-5-one-containing tyrosine aminomutase in enediyne antitumor antibiotic C-1027 biosynthesis
SD Christenson, W Liu, MD Toney, B Shen
Journal of the American Chemical Society 125 (20), 6062-6063, 2003
1302003
Structural and mechanistic analysis of two refined crystal structures of the pyridoxal phosphate-dependent enzyme dialkylglycine decarboxylase
MD Toney, E Hohenester, JW Keller, JN Jansonius
Journal of molecular biology 245 (2), 151-179, 1995
1201995
Controlling reaction specificity in pyridoxal phosphate enzymes
MD Toney
Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1814 (11), 1407-1418, 2011
1112011
NMR studies of solvent-assisted proton transfer in a biologically relevant Schiff base: toward a distinction of geometric and equilibrium H-bond isotope effects
S Sharif, GS Denisov, MD Toney, HH Limbach
Journal of the American Chemical Society 128 (10), 3375-3387, 2006
1112006
Lysine 258 in aspartate aminotransferase: Enforcer of the Circe effect for amino acid substrates and the general-base catalyst for the 1, 3-prototropic shift
MD Toney, JF Kirsch
Biochemistry 32 (6), 1471-1479, 1993
1071993
2.8-. ANG.-resolution crystal structure of an active-site mutant of aspartate aminotransferase from Escherichia coli
DL Smith, SC Almo, MD Toney, D Ringe
Biochemistry 28 (20), 8161-8167, 1989
1021989
Coupling of Functional Hydrogen Bonds in Pyridoxal-5 ‘-phosphate− Enzyme Model Systems Observed by Solid-State NMR Spectroscopy
S Sharif, D Schagen, MD Toney, HH Limbach
Journal of the American Chemical Society 129 (14), 4440-4455, 2007
992007
Crystal structures of unbound and aminooxyacetate-bound Escherichia coli γ-aminobutyrate aminotransferase
W Liu, PE Peterson, RJ Carter, X Zhou, JA Langston, AJ Fisher, ...
Biochemistry 43 (34), 10896-10905, 2004
962004
Aminophosphonate Inhibitors of Dialkylglycine Decarboxylase:  Structural Basis for Slow Binding Inhibition,
W Liu, CJ Rogers, AJ Fisher, MD Toney
Biochemistry 41 (41), 12320-12328, 2002
922002
Crystal structure of true enzymic reaction intermediates: aspartate and glutamate ketimines in aspartate aminotransferase
VN Malashkevich, MD Toney, JN Jansonius
Biochemistry 32 (49), 13451-13462, 1993
881993
NMR Studies of Coupled Low-and High-Barrier Hydrogen Bonds in Pyridoxal-5 ‘-phosphate Model Systems in Polar Solution
S Sharif, GS Denisov, MD Toney, HH Limbach
Journal of the American Chemical Society 129 (19), 6313-6327, 2007
852007
Conservation of mechanism in three chorismate-utilizing enzymes
Z He, KD Stigers Lavoie, PA Bartlett, MD Toney
Journal of the American Chemical Society 126 (8), 2378-2385, 2004
852004
Kinetic analysis of the 4-methylideneimidazole-5-one-containing tyrosine aminomutase in enediyne antitumor antibiotic C-1027 biosynthesis
SD Christenson, W Wu, MA Spies, B Shen, MD Toney
Biochemistry 42 (43), 12708-12718, 2003
792003
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