The pluripotent regulatory circuitry connecting promoters to their long-range interacting elements S Schoenfelder, M Furlan-Magaril, B Mifsud, F Tavares-Cadete, R Sugar, ... Genome research 25 (4), 582-597, 2015 | 458 | 2015 |
A Sox2 distal enhancer cluster regulates embryonic stem cell differentiation potential HY Zhou, Y Katsman, NK Dhaliwal, S Davidson, NN Macpherson, ... Genes & development 28 (24), 2699-2711, 2014 | 183 | 2014 |
Enhancers and super-enhancers have an equivalent regulatory role in embryonic stem cells through regulation of single or multiple genes SD Moorthy, S Davidson, VM Shchuka, G Singh, N Malek-Gilani, ... Genome research 27 (2), 246-258, 2017 | 170 | 2017 |
Kainate receptors coexist in a functional complex with KCC2 and regulate chloride homeostasis in hippocampal neurons V Mahadevan, JC Pressey, BA Acton, P Uvarov, MY Huang, J Chevrier, ... Cell reports 7 (6), 1762-1770, 2014 | 84 | 2014 |
Enhancer–promoter interactions can bypass CTCF-mediated boundaries and contribute to phenotypic robustness S Chakraborty, N Kopitchinski, Z Zuo, A Eraso, P Awasthi, R Chari, A Mitra, ... Nature genetics 55 (2), 280-290, 2023 | 41 | 2023 |
A flexible repertoire of transcription factor binding sites and a diversity threshold determines enhancer activity in embryonic stem cells G Singh, S Mullany, SD Moorthy, R Zhang, T Mehdi, R Tian, AG Duncan, ... Genome Research 31 (4), 564-575, 2021 | 41 | 2021 |
Chromatin dynamics in lineage commitment and cellular reprogramming VM Shchuka, N Malek-Gilani, G Singh, L Langroudi, NK Dhaliwal, ... Genes 6 (3), 641-661, 2015 | 22 | 2015 |
Generating CRISPR/Cas9 mediated monoallelic deletions to study enhancer function in mouse embryonic stem cells SD Moorthy, JA Mitchell JoVE (Journal of Visualized Experiments), e53552, 2016 | 19 | 2016 |
Transcriptional regulation and chromatin architecture maintenance are decoupled functions at the Sox2 locus T Taylor, N Sikorska, VM Shchuka, S Chahar, C Ji, NN Macpherson, ... Genes & Development 36 (11-12), 699-717, 2022 | 15 | 2022 |
Transcriptional enhancers: from prediction to functional assessment on a genome-wide scale IC Tobias, LE Abatti, SD Moorthy, S Mullany, T Taylor, N Khader, ... Genome 64 (4), 426-448, 2021 | 15 | 2021 |
Lymphatic filarial species differentiation using evolutionarily modified tandem repeats: generation of new genetic markers M Sakthidevi, V Murugan, SL Hoti, P Kaliraj Infection, Genetics and Evolution 10 (4), 591-594, 2010 | 9 | 2010 |
Transcriptional regulation and chromatin architecture maintenance are decoupled modular functions at the Sox2 locus T Taylor, N Sikorska, VM Shchuka, S Chahar, C Ji, NN Macpherson, ... biorxiv, 2022.02. 09.479674, 2022 | 3 | 2022 |
Wucherria bancrofti glutathione S-Transferase: Insights into the 2.3 Å resolution X-ray structure and function, a therapeutic target for human lymphatic filariasis PR Prabhu, SD Moorthy, J Madhumathi, SN Pradhan, M Perbandt, ... Biochemical and biophysical research communications 505 (4), 979-984, 2018 | 2 | 2018 |
Functional analysis of a highly conserved abundant larval transcript-2 (alt-2) intron 2 repeat region of lymphatic filarial parasites M Sakthidevi, SL Hoti, P Kaliraj Infection, Genetics and Evolution 24, 177-182, 2014 | 1 | 2014 |
A Proximal Sox2 Enhancer Cluster is Required for the Anterior Regional Identity of Neural Progenitors IC Tobias, SD Moorthy, VM Shchuka, L Langroudi, ZE Gillespie, ... bioRxiv, 2023.11. 09.566464, 2023 | | 2023 |
Supplemental data for: Enhancers and super-enhancers have an equivalent regulatory role in embryonic stem cells through regulation of single or multiple genes SD Moorthy, S Davidson, VM Shchuka, G Singh, N Malek-Gilani, ... | | |