| IL-21R on T cells is critical for sustained functionality and control of chronic viral infection A Fröhlich, J Kisielow, I Schmitz, S Freigang, AT Shamshiev, J Weber, ... Science 324 (5934), 1576-1580, 2009 | 547 | 2009 |
| T cell lipid peroxidation induces ferroptosis and prevents immunity to infection M Matsushita, S Freigang, C Schneider, M Conrad, GW Bornkamm, ... Journal of Experimental Medicine 212 (4), 555-568, 2015 | 492 | 2015 |
| Toll-like receptor engagement converts T-cell autoreactivity into overt autoimmune disease KS Lang, M Recher, T Junt, AA Navarini, NL Harris, S Freigang, ... Nature medicine 11 (2), 138-145, 2005 | 463 | 2005 |
| Immunization of LDL receptor–deficient mice with homologous malondialdehyde-modified and native LDL reduces progression of atherosclerosis by mechanisms other than induction of … S Freigang, S Hörkkö, E Miller, JL Witztum, W Palinski Arteriosclerosis, thrombosis, and vascular biology 18 (12), 1972-1982, 1998 | 399 | 1998 |
| Fatty acid–induced mitochondrial uncoupling elicits inflammasome-independent IL-1α and sterile vascular inflammation in atherosclerosis S Freigang, F Ampenberger, A Weiss, TD Kanneganti, Y Iwakura, ... Nature immunology 14 (10), 1045-1053, 2013 | 345 | 2013 |
| Nrf2 is essential for cholesterol crystal‐induced inflammasome activation and exacerbation of atherosclerosis S Freigang, F Ampenberger, G Spohn, S Heer, AT Shamshiev, J Kisielow, ... European journal of immunology 41 (7), 2040-2051, 2011 | 303 | 2011 |
| Hypergammaglobulinemia and autoantibody induction mechanisms in viral infections L Hunziker, M Recher, AJ Macpherson, A Ciurea, S Freigang, ... Nature immunology 4 (4), 343-349, 2003 | 262 | 2003 |
| Linking immune-mediated arterial inflammation and cholesterol-induced atherosclerosis in a transgenic mouse model B Ludewig, S Freigang, M Jäggi, MO Kurrer, YC Pei, L Vlk, B Odermatt, ... Proceedings of the National Academy of Sciences 97 (23), 12752-12757, 2000 | 178 | 2000 |
| Expansion of protective CD8+ T-cell responses driven by recombinant cytomegaloviruses U Karrer, M Wagner, S Sierro, A Oxenius, H Hengel, T Dumrese, ... Journal of virology 78 (5), 2255-2264, 2004 | 149 | 2004 |
| Deliberate removal of T cell help improves virus-neutralizing antibody production M Recher, KS Lang, L Hunziker, S Freigang, B Eschli, NL Harris, ... Nature immunology 5 (9), 934-942, 2004 | 111 | 2004 |
| Phospholipid oxidation generates potent anti‐inflammatory lipid mediators that mimic structurally related pro‐resolving eicosanoids by activating Nrf2 P Bretscher, J Egger, A Shamshiev, M Trötzmüller, H Köfeler, EM Carreira, ... EMBO molecular medicine 7 (5), 593-607, 2015 | 104 | 2015 |
| Lysosomal recycling terminates CD1d-mediated presentation of short and polyunsaturated variants of the NKT cell lipid antigen αGalCer L Bai, Y Sagiv, Y Liu, S Freigang, KOA Yu, L Teyton, SA Porcelli, ... Proceedings of the National Academy of Sciences 106 (25), 10254-10259, 2009 | 96 | 2009 |
| Maternal immunization programs postnatal immune responses and reduces atherosclerosis in offspring T Yamashita, S Freigang, C Eberle, J Pattison, S Gupta, C Napoli, ... Circulation research 99 (7), E51-E64, 2006 | 91 | 2006 |
| IL-21 restricts virus-driven Treg cell expansion in chronic LCMV infection I Schmitz, C Schneider, A Fröhlich, H Frebel, D Christ, WJ Leonard, ... PLoS Pathog 9 (5), e1003362, 2013 | 88 | 2013 |
| The regulation of inflammation by oxidized phospholipids S Freigang European Journal of Immunology 46 (8), 1818-1825, 2016 | 86 | 2016 |
| TREM-1 links dyslipidemia to inflammation and lipid deposition in atherosclerosis D Zysset, B Weber, S Rihs, J Brasseit, S Freigang, C Riether, Y Banz, ... Nature Communications 7, 13151, 2016 | 84 | 2016 |
| Endogenous neosynthesis vs. cross-presentation of viral antigens for cytotoxic T cell priming S Freigang, D Egger, K Bienz, H Hengartner, RM Zinkernagel Proceedings of the National Academy of Sciences 100 (23), 13477-13482, 2003 | 76 | 2003 |
| Synthesis of Epoxyisoprostanes: Effects in Reducing Secretion of Pro‐inflammatory Cytokines IL‐6 and IL‐12 J Egger, P Bretscher, S Freigang, M Kopf, EM Carreira Angewandte Chemie International Edition 52 (20), 5382-5385, 2013 | 71 | 2013 |
| Extralymphatic virus sanctuaries as a consequence of potent T-cell activation M Recher, KS Lang, A Navarini, L Hunziker, PA Lang, K Fink, S Freigang, ... Nature medicine 13 (11), 1316-1323, 2007 | 70 | 2007 |
| Scavenger receptors target glycolipids for natural killer T cell activation S Freigang, E Landais, V Zadorozhny, L Kain, K Yoshida, Y Liu, S Deng, ... The Journal of clinical investigation 122 (11), 3943-3954, 2012 | 60 | 2012 |
