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monsef benkirane
monsef benkirane
Directeur de recherche CNRS
Adresse e-mail validée de igh.cnrs.fr
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SAMHD1 is the dendritic-and myeloid-cell-specific HIV-1 restriction factor counteracted by Vpx
N Laguette, B Sobhian, N Casartelli, M Ringeard, C Chable-Bessia, ...
Nature 474 (7353), 654-657, 2011
16842011
SAMHD1 restricts the replication of human immunodeficiency virus type 1 by depleting the intracellular pool of deoxynucleoside triphosphates
H Lahouassa, W Daddacha, H Hofmann, D Ayinde, EC Logue, L Dragin, ...
Nature immunology 13 (3), 223-228, 2012
9492012
Suppression of microRNA-silencing pathway by HIV-1 during virus replication
R Triboulet, B Mari, YL Lin, C Chable-Bessia, Y Bennasser, K Lebrigand, ...
Science 315 (5818), 1579-1582, 2007
7982007
Post-activation turn-off of NF-κB-dependent transcription is regulated by acetylation of p65
R Kiernan, V Brès, RWM Ng, MP Coudart, S El Messaoudi, C Sardet, ...
Journal of Biological Chemistry 278 (4), 2758-2766, 2003
7492003
Towards an HIV cure: a global scientific strategy
Nature reviews Immunology 12 (8), 607-614, 2012
6052012
Evidence that HIV-1 encodes an siRNA and a suppressor of RNA silencing
Y Bennasser, SY Le, M Benkirane, KT Jeang
Immunity 22 (5), 607-619, 2005
5632005
HIV‐1 tat transcriptional activity is regulated by acetylation
RE Kiernan, C Vanhulle, L Schiltz, E Adam, H Xiao, F Maudoux, ...
The EMBO journal, 1999
5221999
Mechanism of transdominant inhibition of CCR5-mediated HIV-1 infection by ccr5Δ32
M Benkirane, DY Jin, RF Chun, RA Koup, KT Jeang
Journal of Biological Chemistry 272 (49), 30603-30606, 1997
4931997
International AIDS Society global scientific strategy: towards an HIV cure 2016
SG Deeks, SR Lewin, AL Ross, J Ananworanich, M Benkirane, P Cannon, ...
Nature medicine 22 (8), 839-850, 2016
4872016
Selective CXCR4 antagonism by Tat: Implications for in vivo expansion of coreceptor use by HIV-1
H Xiao, C Neuveut, HL Tiffany, M Benkirane, EA Rich, PM Murphy, ...
Proceedings of the National Academy of Sciences 97 (21), 11466-11471, 2000
4372000
Phosphorylation of SAMHD1 by cyclin A2/CDK1 regulates its restriction activity toward HIV-1
A Cribier, B Descours, ALC Valadao, N Laguette, M Benkirane
Cell reports 3 (4), 1036-1043, 2013
4222013
HIV-1 Tat assembles a multifunctional transcription elongation complex and stably associates with the 7SK snRNP
B Sobhian, N Laguette, A Yatim, M Nakamura, Y Levy, R Kiernan, ...
Molecular cell 38 (3), 439-451, 2010
4092010
SAMHD1 restricts HIV-1 reverse transcription in quiescent CD4+T-cells
B Descours, A Cribier, C Chable-Bessia, D Ayinde, G Rice, Y Crow, ...
Retrovirology 9, 1-8, 2012
3832012
SAMHD1 acts at stalled replication forks to prevent interferon induction
F Coquel, MJ Silva, H Técher, K Zadorozhny, S Sharma, J Nieminuszczy, ...
Nature 557 (7703), 57-61, 2018
3772018
Activation of integrated provirus requires histone acetyltransferase: p300 and P/CAF are coactivators for HIV-1 Tat
M Benkirane, RF Chun, H Xiao, VV Ogryzko, BH Howard, Y Nakatani, ...
Journal of Biological Chemistry 273 (38), 24898-24905, 1998
3641998
Suv39H1 and HP1γ are responsible for chromatin‐mediated HIV‐1 transcriptional silencing and post‐integration latency
I Chéné, E Basyuk, YL Lin, R Triboulet, A Knezevich, C Chable‐Bessia, ...
The EMBO journal 26 (2), 424-435, 2007
3472007
Towards an HBV cure: state-of-the-art and unresolved questions—report of the ANRS workshop on HBV cure
MB Zeisel, J Lucifora, WS Mason, C Sureau, J Beck, M Levrero, M Kann, ...
Gut 64 (8), 1314-1326, 2015
3042015
CD32a is a marker of a CD4 T-cell HIV reservoir harbouring replication-competent proviruses
B Descours, G Petitjean, JL López-Zaragoza, T Bruel, R Raffel, C Psomas, ...
Nature 543 (7646), 564-567, 2017
2902017
Oncogenic potential of TAR RNA binding protein TRBP and its regulatory interaction with RNA‐dependent protein kinase PKR
M Benkirane, C Neuveut, RF Chun, SM Smith, CE Samuel, A Gatignol, ...
The EMBO journal, 1997
2871997
SAMHD1 is mutated recurrently in chronic lymphocytic leukemia and is involved in response to DNA damage
R Clifford, T Louis, P Robbe, S Ackroyd, A Burns, AT Timbs, ...
Blood, The Journal of the American Society of Hematology 123 (7), 1021-1031, 2014
2582014
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