| Integration of external signaling pathways with the core transcriptional network in embryonic stem cells X Chen, H Xu, P Yuan, F Fang, M Huss, VB Vega, E Wong, YL Orlov, ... Cell 133 (6), 1106-1117, 2008 | 2927 | 2008 |
| One thousand plant transcriptomes and the phylogenomics of green plants Nature 574 (7780), 679-685, 2019 | 1192 | 2019 |
| Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst G Guo, M Huss, GQ Tong, C Wang, LL Sun, ND Clarke, P Robson Developmental cell 18 (4), 675-685, 2010 | 940 | 2010 |
| Open chromatin defined by DNaseI and FAIRE identifies regulatory elements that shape cell-type identity L Song, Z Zhang, LL Grasfeder, AP Boyle, PG Giresi, BK Lee, ... Genome research 21 (10), 1757-1767, 2011 | 620 | 2011 |
| A genome-wide RNAi screen reveals determinants of human embryonic stem cell identity NY Chia, YS Chan, B Feng, X Lu, YL Orlov, D Moreau, P Kumar, L Yang, ... Nature 468 (7321), 316-320, 2010 | 541 | 2010 |
| A library of yeast transcription factor motifs reveals a widespread function for Rsc3 in targeting nucleosome exclusion at promoters G Badis, ET Chan, H van Bakel, L Pena-Castillo, D Tillo, K Tsui, ... Molecular cell 32 (6), 878-887, 2008 | 532 | 2008 |
| Towards a rigorous assessment of systems biology models: the DREAM3 challenges RJ Prill, D Marbach, J Saez-Rodriguez, PK Sorger, LG Alexopoulos, ... PloS one 5 (2), e9202, 2010 | 497 | 2010 |
| DNA binding and nucleotide flipping by the human DNA repair protein AGT DS Daniels, TT Woo, KX Luu, DM Noll, ND Clarke, AE Pegg, JA Tainer Nature structural & molecular biology 11 (8), 714-720, 2004 | 360 | 2004 |
| Identification of the uvrA gene product A Sancar, RP Wharton, S Seltzer, BM Kacinski, ND Clarke, WD Rupp Journal of molecular biology 148 (1), 45-62, 1981 | 323 | 1981 |
| Zinc fingers in Caenorhabditis elegans: finding families and probing pathways ND Clarke, JM Berg Science 282 (5396), 2018-2022, 1998 | 266 | 1998 |
| A tetrahedral zinc (II)-binding site introduced into a designed protein L Regan, ND Clarke Biochemistry 29 (49), 10878-10883, 1990 | 256 | 1990 |
| Evaluating methods for isolating total RNA and predicting the success of sequencing phylogenetically diverse plant transcriptomes MTJ Johnson, EJ Carpenter, Z Tian, R Bruskiewich, JN Burris, ... PloS one 7 (11), e50226, 2012 | 250 | 2012 |
| Integrative model of genomic factors for determining binding site selection by estrogen receptor‐α R Joseph, YL Orlov, M Huss, W Sun, S Li Kong, L Ukil, Y Fu Pan, G Li, ... Molecular systems biology 6 (1), 456, 2010 | 200 | 2010 |
| Structural studies of the engrailed homeodomain ND Clarke, CR Kissinger, J Desjarlais, GL Gilliland, CO Pabo Protein Science 3 (10), 1779-1787, 1994 | 193 | 1994 |
| Identification of cis Elements Directing Termination of Yeast Nonpolyadenylated snoRNA Transcripts KL Carroll, DA Pradhan, JA Granek, ND Clarke, JL Corden Molecular and cellular biology 24 (14), 6241-6252, 2004 | 188 | 2004 |
| Whole-genome comparison of Leu3 binding in vitro and in vivo reveals the importance of nucleosome occupancy in target site selection X Liu, CK Lee, JA Granek, ND Clarke, JD Lieb Genome research 16 (12), 1517-1528, 2006 | 170 | 2006 |
| Assessment of CASP7 structure predictions for template free targets R Jauch, HC Yeo, PR Kolatkar, ND Clarke Proteins: Structure, Function, and Bioinformatics 69 (S8), 57-67, 2007 | 163 | 2007 |
| Covariation of residues in the homeodomain sequence family ND Clarke Protein Science 4 (11), 2269-2278, 1995 | 150 | 1995 |
| Dynamic Deposition of Histone Variant H3.3 Accompanies Developmental Remodeling of the Arabidopsis Transcriptome H Wollmann, S Holec, K Alden, ND Clarke, PE Jacques, F Berger PLoS genetics 8 (5), e1002658, 2012 | 146 | 2012 |
| Explicit equilibrium modeling of transcription-factor binding and gene regulation JA Granek, ND Clarke Genome biology 6, 1-10, 2005 | 145 | 2005 |
