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Marcus O. Muench Ph.D.
Marcus O. Muench Ph.D.
Senior Scientist, Vitalant Research Institute
Adresse e-mail validée de vitalant.org - Page d'accueil
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Année
Maternal alloantigens promote the development of tolerogenic fetal regulatory T cells in utero
JE Mold, J Michaëlsson, TD Burt, MO Muench, KP Beckerman, MP Busch, ...
Science 322 (5907), 1562-1565, 2008
9402008
Ligand for FLT3/FLK2 receptor tyrosine kinase regulates growth of haematopoietic stem cells and is encoded by variant RNAs
C Hannum, J Culpepper, D Campbell, T McClanahan, S Zurawski, ...
Nature 368 (6472), 643-648, 1994
6111994
Seamless gene correction of β-thalassemia mutations in patient-specific iPSCs using CRISPR/Cas9 and piggyBac
F Xie, L Ye, JC Chang, AI Beyer, J Wang, MO Muench, YW Kan
Genome research 24 (9), 1526-1533, 2014
5462014
Differential downregulation of ACE2 by the spike proteins of severe acute respiratory syndrome coronavirus and human coronavirus NL63
I Glowacka, S Bertram, P Herzog, S Pfefferle, I Steffen, MO Muench, ...
Journal of virology 84 (2), 1198-1205, 2010
5362010
Seamless modification of wild-type induced pluripotent stem cells to the natural CCR5Δ32 mutation confers resistance to HIV infection
L Ye, J Wang, AI Beyer, F Teque, TJ Cradick, Z Qi, JC Chang, G Bao, ...
Proceedings of the National Academy of Sciences 111 (26), 9591-9596, 2014
4112014
Identification of a common T/natural killer cell progenitor in human fetal thymus.
MJ Sanchez, MO Muench, MG Roncarolo, LL Lanier, JH Phillips
The Journal of experimental medicine 180 (2), 569-576, 1994
3511994
Whole-genome fingerprint of the DNA methylome during human B cell differentiation
M Kulis, A Merkel, S Heath, AC Queirós, RP Schuyler, G Castellano, ...
Nature genetics 47 (7), 746-756, 2015
3132015
Exosomes from red blood cell units bind to monocytes and induce proinflammatory cytokines, boosting T-cell responses in vitro
A Danesh, HC Inglis, RP Jackman, S Wu, X Deng, MO Muench, ...
Blood, The Journal of the American Society of Hematology 123 (5), 687-696, 2014
2572014
Genome editing using CRISPR-Cas9 to create the HPFH genotype in HSPCs: An approach for treating sickle cell disease and β-thalassemia
L Ye, J Wang, Y Tan, AI Beyer, F Xie, MO Muench, YW Kan
Proceedings of the National Academy of Sciences 113 (38), 10661-10665, 2016
2042016
Bone marrow transplantation with interleukin-1 plus kit-ligand ex vivo expanded bone marrow accelerates hematopoietic reconstitution in mice without the loss of stem cell …
MO Muench, MT Firpo, MA Moore
Blood 81 (12), 3463, 1993
1861993
Expression of CD33, CD38, and HLA-DR on CD34+ human fetal liver progenitors with a high proliferative potential
MO Muench, J Cupp, J Polakoff, MG Roncarolo
1521994
Interactions among colony-stimulating factors, IL-1 beta, IL-6, and kit-ligand in the regulation of primitive murine hematopoietic cells.
MO Muench, JG Schneider, MA Moore
Experimental hematology 20 (3), 339-349, 1992
1471992
A neutralizing monoclonal antibody targeting the acid-sensitive region in chikungunya virus E2 protects from disease
S Selvarajah, NR Sexton, KM Kahle, RH Fong, KA Mattia, J Gardner, K Lu, ...
PLoS neglected tropical diseases 7 (9), e2423, 2013
1282013
Phenotypic and functional analysis of T-cell precursors in the human fetal liver and thymus: CD7 expression in the early stages of T-and myeloid-cell development
A Barcena, MO Muench, AH Galy, J Cupp, MG Roncarolo, JH Phillips, ...
1191993
FLK-2/FLT-3 ligand regulates the growth of early myeloid progenitors isolated from human fetal liver
MO Muench, MG Roncarolo, S Menon, Y Xu, R Kastelein, S Zurawski, ...
Blood 85 (4), 963-972, 1995
1171995
The FLK2/FLT3 ligand synergizes with interleukin-7 in promoting stromal-cell-independent expansion and differentiation of human fetal pro-B cells in vitro
R Namikawa, MO Muench, JE De Vries, MG Roncarolo
Blood 87 (5), 1881-1890, 1996
1161996
Searching for common stem cells of the hepatic and hematopoietic systems in the human fetal liver: CD34+ cytokeratin 7/8+ cells express markers for stellate cells
DL Suskind, MO Muench
Journal of Hepatology 40 (2), 261-268, 2004
1132004
A global DNA methylation and gene expression analysis of early human B-cell development reveals a demethylation signature and transcription factor network
ST Lee, Y Xiao, MO Muench, J Xiao, ME Fomin, JK Wiencke, S Zheng, ...
Nucleic acids research 40 (22), 11339-11351, 2012
1092012
Polysialic acid, a glycan with highly restricted expression, is found on human and murine leukocytes and modulates immune responses
PM Drake, JK Nathan, CM Stock, PV Chang, MO Muench, D Nakata, ...
The Journal of Immunology 181 (10), 6850-6858, 2008
1072008
SOX2 regulates acinar cell development in the salivary gland
E Emmerson, AJ May, S Nathan, N Cruz-Pacheco, CO Lizama, ...
Elife 6, e26620, 2017
1052017
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