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Christophe Léger
Christophe Léger
CNRS, Aix Marseille Université, France
Adresse e-mail validée de imm.cnrs.fr - Page d'accueil
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Architecture of succinate dehydrogenase and reactive oxygen species generation
V Yankovskaya, R Horsefield, S Tornroth, C Luna-Chavez, H Miyoshi, ...
Science 299 (5607), 700-704, 2003
11112003
Direct electrochemistry of redox enzymes as a tool for mechanistic studies
C Léger, P Bertrand
Chemical Reviews 108 (7), 2379-2438, 2008
8012008
Enzyme electrokinetics: Using protein film voltammetry to investigate redox enzymes and their mechanisms
C Léger, SJ Elliott, KR Hoke, LJC Jeuken, AK Jones, FA Armstrong
Biochemistry 42 (29), 8653-8662, 2003
3302003
Effect of a dispersion of interfacial electron transfer rates on steady state catalytic electron transport in [NiFe]-hydrogenase and other enzymes
C Léger, AK Jones, SPJ Albracht, FA Armstrong
The Journal of Physical Chemistry B 106 (50), 13058-13063, 2002
2792002
Relating diffusion along the substrate tunnel and oxygen sensitivity in hydrogenase
PP Liebgott, F Leroux, B Burlat, S Dementin, C Baffert, T Lautier, ...
Nature chemical biology 6 (1), 63-70, 2010
2432010
Experimental approaches to kinetics of gas diffusion in hydrogenase
F Leroux, S Dementin, B Burlat, L Cournac, A Volbeda, S Champ, L Martin, ...
Proceedings of the National Academy of Sciences 105 (32), 11188-11193, 2008
1892008
Inhibition and aerobic inactivation kinetics of Desulfovibrio fructosovorans NiFe hydrogenase studied by protein film voltammetry
C Léger, S Dementin, P Bertrand, M Rousset, B Guigliarelli
Journal of the American Chemical Society 126 (38), 12162-12172, 2004
1752004
Membrane-Bound Hydrogenase I from the Hyperthermophilic Bacterium Aquifex aeolicus: Enzyme Activation, Redox Intermediates and Oxygen Tolerance
ME Pandelia, V Fourmond, P Tron-Infossi, E Lojou, P Bertrand, C Léger, ...
Journal of the American Chemical Society 132 (20), 6991-7004, 2010
1732010
Enzyme electrokinetics: hydrogen evolution and oxidation by Allochromatium vinosum [NiFe]-hydrogenase
C Léger, AK Jones, W Roseboom, SPJ Albracht, FA Armstrong
Biochemistry 41 (52), 15736-15746, 2002
1372002
SOAS: A free program to analyze electrochemical data and other one-dimensional signals
V Fourmond, K Hoke, HA Heering, C Baffert, F Leroux, P Bertrand, ...
Bioelectrochemistry 76 (1-2), 141-147, 2009
1342009
Introduction of methionines in the gas channel makes [NiFe] hydrogenase aero-tolerant
S Dementin, F Leroux, L Cournac, AL Lacey, A Volbeda, C Leger, B Burlat, ...
Journal of the American Chemical Society 131 (29), 10156-10164, 2009
1292009
Mechanism of O2 diffusion and reduction in FeFe hydrogenases
A Kubas, C Orain, D De Sancho, L Saujet, M Sensi, C Gauquelin, ...
Nature chemistry 9 (1), 88-95, 2017
1252017
Understanding and tuning the catalytic bias of hydrogenase
A Abou Hamdan, S Dementin, PP Liebgott, O Gutierrez-Sanz, P Richaud, ...
Journal of the American Chemical Society 134 (20), 8368-8371, 2012
1232012
Original design of an oxygen-tolerant [NiFe] hydrogenase: major effect of a valine-to-cysteine mutation near the active site
PP Liebgott, AL de Lacey, B Burlat, L Cournac, P Richaud, M Brugna, ...
Journal of the American Chemical Society 133 (4), 986-997, 2011
1162011
Changing the ligation of the distal [4Fe4S] cluster in NiFe hydrogenase impairs inter-and intramolecular electron transfers
S Dementin, V Belle, P Bertrand, B Guigliarelli, G Adryanczyk-Perrier, ...
Journal of the American Chemical Society 128 (15), 5209-5218, 2006
1162006
Hydrogen‐activating enzymes: Activity does not correlate with oxygen sensitivity
C Baffert, M Demuez, L Cournac, B Burlat, B Guigliarelli, P Bertrand, ...
Angewandte Chemie International Edition 47 (11), 2052-2054, 2008
1122008
Fast voltammetric studies of the kinetics and energetics of coupled electron-transfer reactions in proteins
FA Armstrong, R Camba, HA Heering, J Hirst, LJC Jeuken, AK Jones, ...
Faraday discussions 116, 191-203, 2000
1072000
The oxidative inactivation of FeFe hydrogenase reveals the flexibility of the H-cluster
V Fourmond, C Greco, K Sybirna, C Baffert, PH Wang, P Ezanno, ...
Nature chemistry 6 (4), 336-342, 2014
1062014
Determination of an optimal potential window for catalysis by E. coli dimethyl sulfoxide reductase and hypothesis on the role of Mo (V) in the reaction pathway
K Heffron, C Léger, RA Rothery, JH Weiner, FA Armstrong
Biochemistry 40 (10), 3117-3126, 2001
1042001
Enzyme electrokinetics: energetics of succinate oxidation by fumarate reductase and succinate dehydrogenase
C Léger, K Heffron, HR Pershad, E Maklashina, C Luna-Chavez, ...
Biochemistry 40 (37), 11234-11245, 2001
992001
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