Inducible apoptosis as a safety switch for adoptive cell therapy A Di Stasi, SK Tey, G Dotti, Y Fujita, A Kennedy-Nasser, C Martinez, ... New England Journal of Medicine 365 (18), 1673-1683, 2011 | 1590 | 2011 |
An inducible caspase 9 safety switch for T-cell therapy KC Straathof, MA Pule, P Yotnda, G Dotti, EF Vanin, MK Brenner, ... Blood 105 (11), 4247-4254, 2005 | 804 | 2005 |
A chimeric T cell antigen receptor that augments cytokine release and supports clonal expansion of primary human T cells MA Pulè, KC Straathof, G Dotti, HE Heslop, CM Rooney, MK Brenner Molecular Therapy 12 (5), 933-941, 2005 | 577 | 2005 |
Cytotoxic T Lymphocyte Therapy for Epstein-Barr Virus+ Hodgkin's Disease CM Bollard, L Aguilar, KC Straathof, B Gahn, MH Huls, A Rousseau, ... The Journal of experimental medicine 200 (12), 1623-1633, 2004 | 504 | 2004 |
Treatment of nasopharyngeal carcinoma with Epstein-Barr virus–specific T lymphocytes KCM Straathof, CM Bollard, U Popat, MH Huls, T Lopez, MC Morriss, ... Blood 105 (5), 1898-1904, 2005 | 455 | 2005 |
A highly compact epitope-based marker/suicide gene for easier and safer T-cell therapy B Philip, E Kokalaki, L Mekkaoui, S Thomas, K Straathof, B Flutter, ... Blood, The Journal of the American Society of Hematology 124 (8), 1277-1287, 2014 | 432 | 2014 |
Complete responses of relapsed lymphoma following genetic modification of tumor-antigen presenting cells and T-lymphocyte transfer CM Bollard, S Gottschalk, AM Leen, H Weiss, KC Straathof, G Carrum, ... Blood, The Journal of the American Society of Hematology 110 (8), 2838-2845, 2007 | 341 | 2007 |
Effect of inhaled steroids on airway hyperresponsiveness, sputum eosinophils, and exhaled nitric oxide levels in patients with asthma ELJ van Rensen, KCM Straathof, MA Veselic-Charvat, AH Zwinderman, ... Thorax 54 (5), 403-408, 1999 | 341 | 1999 |
Adoptive transfer of EBV-specific T cells results in sustained clinical responses in patients with locoregional nasopharyngeal carcinoma CU Louis, K Straathof, CM Bollard, S Ennamuri, C Gerken, TT Lopez, ... Journal of immunotherapy 33 (9), 983-990, 2010 | 267 | 2010 |
Natural T‐helper immunity against human papillomavirus type 16 (hpv16) e7–derived peptide epitopes in patients with hpv16‐positive cervical lesions: identification of 3 human … SH van der Burg, ME Ressing, KMC Kwappenberg, A de Jong, ... International journal of cancer 91 (5), 612-618, 2001 | 182 | 2001 |
Intratumoral IL-12 delivery empowers CAR-T cell immunotherapy in a pre-clinical model of glioblastoma G Agliardi, AR Liuzzi, A Hotblack, D De Feo, N Núñez, CL Stowe, ... Nature communications 12 (1), 444, 2021 | 174 | 2021 |
Human cytotoxic T lymphocytes with reduced sensitivity to Fas-induced apoptosis G Dotti, B Savoldo, M Pule, KC Straathof, E Biagi, E Yvon, S Vigouroux, ... Blood 105 (12), 4677-4684, 2005 | 151 | 2005 |
Antitumor activity without on-target off-tumor toxicity of GD2–chimeric antigen receptor T cells in patients with neuroblastoma K Straathof, B Flutter, R Wallace, N Jain, T Loka, S Depani, G Wright, ... Science Translational Medicine 12 (571), eabd6169, 2020 | 136 | 2020 |
Enhancing the in vivo expansion of adoptively transferred EBV-specific CTL with lymphodepleting CD45 monoclonal antibodies in NPC patients CU Louis, K Straathof, CM Bollard, C Gerken, MH Huls, MV Gresik, ... Blood, The Journal of the American Society of Hematology 113 (11), 2442-2450, 2009 | 133 | 2009 |
The generation and characterization of LMP2-specific CTLs for use as adoptive transfer from patients with relapsed EBV-positive Hodgkin disease CM Bollard, KCM Straathof, MH Huls, A Leen, K Lacuesta, A Davis, ... Journal of Immunotherapy 27 (4), 317-327, 2004 | 132 | 2004 |
Embryonal precursors of Wilms tumor THH Coorens, TD Treger, R Al-Saadi, L Moore, MGB Tran, TJ Mitchell, ... Science 366 (6470), 1247-1251, 2019 | 127 | 2019 |
Haemopoietic stem-cell transplantation with antibody-based minimal-intensity conditioning: a phase 1/2 study KC Straathof, K Rao, M Eyrich, G Hale, P Bird, E Berrie, L Brown, ... The Lancet 374 (9693), 912-920, 2009 | 121 | 2009 |
Generation of EBV-specific cytotoxic T cells that are resistant to calcineurin inhibitors for the treatment of posttransplantation lymphoproliferative disease J Brewin, C Mancao, K Straathof, H Karlsson, S Samarasinghe, ... Blood, The Journal of the American Society of Hematology 114 (23), 4792-4803, 2009 | 117 | 2009 |
Characterization of latent membrane protein 2 specificity in CTL lines from patients with EBV-positive nasopharyngeal carcinoma and lymphoma KC Straathof, AM Leen, EL Buza, G Taylor, MH Huls, HE Heslop, ... The Journal of Immunology 175 (6), 4137-4147, 2005 | 99 | 2005 |
Tumor to normal single-cell mRNA comparisons reveal a pan-neuroblastoma cancer cell G Kildisiute, WM Kholosy, MD Young, K Roberts, R Elmentaite, ... Science advances 7 (6), eabd3311, 2021 | 97 | 2021 |