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| Minimum information about a biosynthetic gene cluster MH Medema, R Kottmann, P Yilmaz, M Cummings, JB Biggins, K Blin, ... Nature chemical biology 11 (9), 625-631, 2015 | 840 | 2015 |
| Towards the sustainable discovery and development of new antibiotics M Miethke, M Pieroni, T Weber, M Brönstrup, P Hammann, L Halby, ... Nature Reviews Chemistry 5 (10), 726-749, 2021 | 562 | 2021 |
| Identification of a bioactive 51-membered macrolide complex by activation of a silent polyketide synthase in Streptomyces ambofaciens L Laureti, L Song, S Huang, C Corre, P Leblond, GL Challis, B Aigle Proceedings of the National Academy of Sciences 108 (15), 6258-6263, 2011 | 391 | 2011 |
| Evolution of the Terminal Regions of the Streptomyces Linear Chromosome F Choulet, B Aigle, A Gallois, S Mangenot, C Gerbaud, C Truong, ... Molecular Biology and Evolution 23 (12), 2361-2369, 2006 | 129 | 2006 |
| Genome mining of Streptomyces ambofaciens B Aigle, S Lautru, D Spiteller, JS Dickschat, GL Challis, P Leblond, ... Journal of Industrial Microbiology and Biotechnology 41 (2), 251-263, 2014 | 119 | 2014 |
| Characterization and Manipulation of the Pathway-Specific Late Regulator AlpW Reveals Streptomyces ambofaciens as a New Producer of Kinamycins R Bunet, L Song, MV Mendes, C Corre, L Hotel, N Rouhier, X Framboisier, ... Journal of Bacteriology 193 (5), 1142-1153, 2011 | 117 | 2011 |
| Functional Angucycline-Like Antibiotic Gene Cluster in the Terminal Inverted Repeats of the Streptomyces ambofaciens Linear Chromosome X Pang, B Aigle, JM Girardet, S Mangenot, JL Pernodet, B Decaris, ... Antimicrobial agents and chemotherapy 48 (2), 575-588, 2004 | 83 | 2004 |
| Pseudomonas fluorescens pirates both ferrioxamine and ferricoelichelin siderophores from Streptomyces ambofaciens J Galet, A Deveau, L Hôtel, P Frey-Klett, P Leblond, B Aigle Applied and Environmental Microbiology 81 (9), 3132-3141, 2015 | 76 | 2015 |
| Involvement of AlpV, a New Member of the Streptomyces Antibiotic Regulatory Protein Family, in Regulation of the Duplicated Type II Polyketide Synthase alp Gene Cluster in … B Aigle, X Pang, B Decaris, P Leblond Journal of bacteriology 187 (7), 2491-2500, 2005 | 59 | 2005 |
| Waking up Streptomyces secondary metabolism by constitutive expression of activators or genetic disruption of repressors B Aigle, C Corre Methods in enzymology 517, 343-366, 2012 | 57 | 2012 |
| A single amino acid substitution in region 1.2 of the principal σ factor of Streptomyces coelicolor A3 (2) results in pleiotropic loss of antibiotic production B Aigle, A Wietzorrek, E Takano, MJ Bibb Molecular microbiology 37 (5), 995-1004, 2002 | 51 | 2002 |
| Role of secondary metabolites in the interaction between Pseudomonas fluorescens and soil microorganisms under iron-limited conditions A Deveau, H Gross, B Palin, S Mehnaz, M Schnepf, P Leblond, ... FEMS microbiology ecology 92 (8), fiw107, 2016 | 49 | 2016 |
| Comparative Genomics among Closely Related Streptomyces Strains Revealed Specialized Metabolite Biosynthetic Gene Cluster Diversity CM Vicente, A Thibessard, JN Lorenzi, M Benhadj, L Hôtel, ... Antibiotics 7 (4), 86, 2018 | 44 | 2018 |
| A single Sfp-type phosphopantetheinyl transferase plays a major role in the biosynthesis of PKS and NRPS derived metabolites in Streptomyces ambofaciens ATCC23877 R Bunet, R Riclea, L Laureti, L Hotel, C Paris, JM Girardet, D Spiteller, ... PLoS One 9 (1), e87607, 2014 | 44 | 2014 |
| Regulation of the Synthesis of the Angucyclinone Antibiotic Alpomycin in Streptomyces ambofaciens by the Autoregulator Receptor AlpZ and Its Specific Ligand R Bunet, MV Mendes, N Rouhier, X Pang, L Hotel, P Leblond, B Aigle Journal of bacteriology 190 (9), 3293-3305, 2008 | 44 | 2008 |
| End‐to‐end fusion of linear deleted chromosomes initiates a cycle of genome instability in Streptomyces ambofaciens T Wenner, V Roth, G Fischer, C Fourrier, B Aigle, B Decaris, P Leblond Molecular microbiology 50 (2), 411-425, 2003 | 44 | 2003 |
| Kinamycin biosynthesis employs a conserved pair of oxidases for B-ring contraction B Wang, J Ren, L Li, F Guo, G Pan, G Ai, B Aigle, K Fan, K Yang Chemical communications 51 (42), 8845-8848, 2015 | 42 | 2015 |
| Identification of Alp1U and Lom6 as epoxy hydrolases and implications for kinamycin and lomaiviticin biosynthesis B Wang, F Guo, J Ren, G Ai, B Aigle, K Fan, K Yang Nature Communications 6 (1), 7674, 2015 | 39 | 2015 |
| Dynamics of the compartmentalized Streptomyces chromosome during metabolic differentiation VS Lioy, JN Lorenzi, S Najah, T Poinsignon, H Leh, C Saulnier, B Aigle, ... Nature communications 12 (1), 5221, 2021 | 38 | 2021 |
