Bruno Canard
Bruno Canard
Directeur de Recherches CNRS, AMU
Adresse e-mail validée de afmb.univ-mrs.fr - Page d'accueil
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The spike glycoprotein of the new coronavirus 2019-nCoV contains a furin-like cleavage site absent in CoV of the same clade
B Coutard, C Valle, X de Lamballerie, B Canard, NG Seidah, E Decroly
Antiviral research 176, 104742, 2020
9692020
SAMHD1 restricts the replication of human immunodeficiency virus type 1 by depleting the intracellular pool of deoxynucleoside triphosphates
H Lahouassa, W Daddacha, H Hofmann, D Ayinde, EC Logue, L Dragin, ...
Nature immunology 13 (3), 223-228, 2012
7742012
An RNA cap (nucleoside‐2′‐O‐)‐methyltransferase in the flavivirus RNA polymerase NS5: crystal structure and functional characterization
MP Egloff, D Benarroch, B Selisko, JL Romette, B Canard
The EMBO journal 21 (11), 2757-2768, 2002
6342002
Assessing protein disorder and induced folding
V Receveur‐Bréchot, JM Bourhis, VN Uversky, B Canard, S Longhi
Proteins: Structure, Function, and Bioinformatics 62 (1), 24-45, 2006
4502006
Discovery of an RNA virus 3′→ 5′ exoribonuclease that is critically involved in coronavirus RNA synthesis
E Minskaia, T Hertzig, AE Gorbalenya, V Campanacci, C Cambillau, ...
Proceedings of the National Academy of Sciences 103 (13), 5108-5113, 2006
4392006
Crystal structure of the dengue virus RNA-dependent RNA polymerase catalytic domain at 1.85-angstrom resolution
TL Yap, T Xu, YL Chen, H Malet, MP Egloff, B Canard, SG Vasudevan, ...
Journal of virology 81 (9), 4753-4765, 2007
3902007
One severe acute respiratory syndrome coronavirus protein complex integrates processive RNA polymerase and exonuclease activities
L Subissi, CC Posthuma, A Collet, JC Zevenhoven-Dobbe, ...
Proceedings of the National Academy of Sciences 111 (37), E3900-E3909, 2014
3162014
A practical overview of protein disorder prediction methods
F Ferron, S Longhi, B Canard, D Karlin
Proteins: Structure, Function, and Bioinformatics 65 (1), 1-14, 2006
3152006
Structure and functionality in flavivirus NS-proteins: perspectives for drug design
M Bollati, K Alvarez, R Assenberg, C Baronti, B Canard, S Cook, ...
Antiviral research 87 (2), 125-148, 2010
2992010
The C-terminal domain of the measles virus nucleoprotein is intrinsically disordered and folds upon binding to the C-terminal moiety of the phosphoprotein
S Longhi, V Receveur-Bréchot, D Karlin, K Johansson, H Darbon, ...
Journal of Biological Chemistry 278 (20), 18638-18648, 2003
2962003
Conventional and unconventional mechanisms for capping viral mRNA
E Decroly, F Ferron, J Lescar, B Canard
Nature Reviews Microbiology 10 (1), 51-65, 2012
2802012
The severe acute respiratory syndrome-coronavirus replicative protein nsp9 is a single-stranded RNA-binding subunit unique in the RNA virus world
MP Egloff, F Ferron, V Campanacci, S Longhi, C Rancurel, H Dutartre, ...
Proceedings of the National Academy of Sciences 101 (11), 3792-3796, 2004
2572004
A second, non‐canonical RNA‐dependent RNA polymerase in SARS Coronavirus
I Imbert, JC Guillemot, JM Bourhis, C Bussetta, B Coutard, MP Egloff, ...
The EMBO journal 25 (20), 4933-4942, 2006
2472006
Crystal structure of the RNA polymerase domain of the West Nile virus non-structural protein 5
H Malet, MP Egloff, B Selisko, RE Butcher, PJ Wright, M Roberts, A Gruez, ...
Journal of Biological Chemistry 282 (14), 10678-10689, 2007
2352007
Structural and functional basis for ADP-ribose and poly (ADP-ribose) binding by viral macro domains
MP Egloff, H Malet, Á Putics, M Heinonen, H Dutartre, A Frangeul, ...
Journal of virology 80 (17), 8493-8502, 2006
2322006
Towards the design of antiviral inhibitors against flaviviruses: the case for the multifunctional NS3 protein from Dengue virus as a target
J Lescar, D Luo, T Xu, A Sampath, SP Lim, B Canard, SG Vasudevan
Antiviral research 80 (2), 94-101, 2008
2192008
In vitro reconstitution of SARS-coronavirus mRNA cap methylation
M Bouvet, C Debarnot, I Imbert, B Selisko, EJ Snijder, B Canard, ...
PLoS Pathog 6 (4), e1000863, 2010
2132010
Crystal structure and functional analysis of the SARS-coronavirus RNA cap 2′-O-methyltransferase nsp10/nsp16 complex
E Decroly, C Debarnot, F Ferron, M Bouvet, B Coutard, I Imbert, L Gluais, ...
PLoS Pathog 7 (5), e1002059, 2011
2102011
Coronavirus nonstructural protein 16 is a cap-0 binding enzyme possessing (nucleoside-2′ O)-methyltransferase activity
E Decroly, I Imbert, B Coutard, M Bouvet, B Selisko, K Alvarez, ...
Journal of virology 82 (16), 8071-8084, 2008
2042008
The crystal structures of Chikungunya and Venezuelan equine encephalitis virus nsP3 macro domains define a conserved adenosine binding pocket
H Malet, B Coutard, S Jamal, H Dutartre, N Papageorgiou, M Neuvonen, ...
Journal of virology 83 (13), 6534-6545, 2009
2012009
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