Bruno Canard
Bruno Canard
Directeur de Recherches CNRS, AMU
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SAMHD1 restricts the replication of human immunodeficiency virus type 1 by depleting the intracellular pool of deoxynucleoside triphosphates
H Lahouassa, W Daddacha, H Hofmann, D Ayinde, EC Logue, L Dragin, ...
Nature immunology 13 (3), 223-228, 2012
An RNA cap (nucleoside‐2′‐O‐)‐methyltransferase in the flavivirus RNA polymerase NS5: crystal structure and functional characterization
MP Egloff, D Benarroch, B Selisko, JL Romette, B Canard
The EMBO journal 21 (11), 2757-2768, 2002
Assessing protein disorder and induced folding
V Receveur‐Bréchot, JM Bourhis, VN Uversky, B Canard, S Longhi
Proteins: Structure, Function, and Bioinformatics 62 (1), 24-45, 2006
Crystal structure of the dengue virus RNA-dependent RNA polymerase catalytic domain at 1.85-angstrom resolution
TL Yap, T Xu, YL Chen, H Malet, MP Egloff, B Canard, SG Vasudevan, ...
Journal of virology 81 (9), 4753-4765, 2007
The spike glycoprotein of the new coronavirus 2019-nCoV contains a furin-like cleavage site absent in CoV of the same clade
B Coutard, C Valle, X de Lamballerie, B Canard, NG Seidah, E Decroly
Antiviral research 176, 104742, 2020
Discovery of an RNA virus 3′→ 5′ exoribonuclease that is critically involved in coronavirus RNA synthesis
E Minskaia, T Hertzig, AE Gorbalenya, V Campanacci, C Cambillau, ...
Proceedings of the National Academy of Sciences 103 (13), 5108-5113, 2006
A practical overview of protein disorder prediction methods
F Ferron, S Longhi, B Canard, D Karlin
Proteins: Structure, Function, and Bioinformatics 65 (1), 1-14, 2006
The C-terminal domain of the measles virus nucleoprotein is intrinsically disordered and folds upon binding to the C-terminal moiety of the phosphoprotein
S Longhi, V Receveur-Bréchot, D Karlin, K Johansson, H Darbon, ...
Journal of Biological Chemistry 278 (20), 18638-18648, 2003
Structure and functionality in flavivirus NS-proteins: perspectives for drug design
M Bollati, K Alvarez, R Assenberg, C Baronti, B Canard, S Cook, ...
Antiviral research 87 (2), 125-148, 2010
Conventional and unconventional mechanisms for capping viral mRNA
E Decroly, F Ferron, J Lescar, B Canard
Nature Reviews Microbiology 10 (1), 51-65, 2012
Crystal structure of the RNA polymerase domain of the West Nile virus non-structural protein 5
H Malet, MP Egloff, B Selisko, RE Butcher, PJ Wright, M Roberts, A Gruez, ...
Journal of Biological Chemistry 282 (14), 10678-10689, 2007
Towards the design of antiviral inhibitors against flaviviruses: the case for the multifunctional NS3 protein from Dengue virus as a target
J Lescar, D Luo, T Xu, A Sampath, SP Lim, B Canard, SG Vasudevan
Antiviral research 80 (2), 94-101, 2008
Structural and functional basis for ADP-ribose and poly (ADP-ribose) binding by viral macro domains
MP Egloff, H Malet, Á Putics, M Heinonen, H Dutartre, A Frangeul, ...
Journal of virology 80 (17), 8493-8502, 2006
The severe acute respiratory syndrome-coronavirus replicative protein nsp9 is a single-stranded RNA-binding subunit unique in the RNA virus world
MP Egloff, F Ferron, V Campanacci, S Longhi, C Rancurel, H Dutartre, ...
Proceedings of the National Academy of Sciences 101 (11), 3792-3796, 2004
A second, non‐canonical RNA‐dependent RNA polymerase in SARS Coronavirus
I Imbert, JC Guillemot, JM Bourhis, C Bussetta, B Coutard, MP Egloff, ...
The EMBO journal 25 (20), 4933-4942, 2006
The enterotoxin gene (cpe) of Clostridium perfringens can be chromosomal or plasmid‐borne
E Cornillot, B Saint‐Joanis, G Daube, S Katayama, PE Granum, B Canard, ...
Molecular microbiology 15 (4), 639-647, 1995
Mechanistic basis for reduced viral and enzymatic fitness of HIV-1 reverse transcriptase containing both K65R and M184V mutations
J Deval, KL White, MD Miller, NT Parkin, J Courcambeck, P Halfon, ...
Journal of Biological Chemistry 279 (1), 509-516, 2004
The RNA helicase, nucleotide 5′-triphosphatase, and RNA 5′-triphosphatase activities of Dengue virus protein NS3 are Mg2+-dependent and require a functional Walker B motif in …
D Benarroch, B Selisko, GA Locatelli, G Maga, JL Romette, B Canard
Virology 328 (2), 208-218, 2004
The crystal structures of Chikungunya and Venezuelan equine encephalitis virus nsP3 macro domains define a conserved adenosine binding pocket
H Malet, B Coutard, S Jamal, H Dutartre, N Papageorgiou, M Neuvonen, ...
Journal of virology 83 (13), 6534-6545, 2009
Genome organization of the anaerobic pathogen Clostridium perfringens
B Canard, ST Cole
Proceedings of the National Academy of Sciences 86 (17), 6676-6680, 1989
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