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Chintan Savla
Chintan Savla
Scientist at Bristol Myers Squibb
Verified email at osu.edu
Title
Cited by
Cited by
Year
Purification of Lumbricus terrestris Mega-Hemoglobin for Diverse Oxygen Therapeutic Applications
C Savla, C Munoz, R Hickey, M Belicak, C Gilbert, P Cabrales, AF Palmer
ACS biomaterials science & engineering 6 (9), 4957-4968, 2020
182020
Structural stability and biophysical properties of the mega-protein erythrocruorin are regulated by polyethylene glycol surface coverage
C Savla, AF Palmer
Biomacromolecules 22 (5), 2081-2093, 2021
102021
Poly (ethylene glycol) surface-conjugated apohemoglobin as a synthetic heme scavenger
IS Pires, C Savla, AF Palmer
Biomacromolecules 21 (6), 2155-2164, 2020
102020
Comprehensive characterization of tense and relaxed quaternary state glutaraldehyde polymerized bovine hemoglobin as a function of cross‐link density
X Gu, C Bolden‐Rush, CT Cuddington, DA Belcher, C Savla, IS Pires, ...
Biotechnology and bioengineering 117 (8), 2362-2376, 2020
92020
Tangential flow filtration facilitated fractionation and PEGylation of low and high‐molecular weight polymerized hemoglobins and their biophysical properties
X Gu, C Savla, AF Palmer
Biotechnology and bioengineering 119 (1), 176-186, 2022
72022
Purification and analysis of a protein cocktail capable of scavenging cell‐free hemoglobin, heme, and iron
IS Pires, K Govender, CJ Munoz, AT Williams, QT O'Boyle, C Savla, ...
Transfusion 61 (6), 1894-1907, 2021
62021
Enhanced photodynamic therapy using the apohemoglobin-haptoglobin complex as a carrier of aluminum phthalocyanine
IS Pires, QT O’Boyle, CJ Munoz, C Savla, P Cabrales, AF Palmer
ACS Applied Bio Materials 3 (7), 4495-4506, 2020
42020
Photocatalytic synthesis of a polydopamine-coated acellular mega-hemoglobin as a potential oxygen therapeutic with antioxidant properties
E Pozy, C Savla, AF Palmer
Biomacromolecules 24 (5), 2022-2029, 2023
22023
Lyophilized annelid mega-hemoglobin retains its’ quaternary structure and oxygen equilibrium properties after room temperature storage for over 6 months
C Savla, AF Palmer
Plos one 17 (2), e0263996, 2022
22022
Colloidally stable heme-albumin complexes and methods of making and using thereof
A Palmer, C Savla
US Patent WO2023201107A1, 2023
2023
Biocompatibility of the oxygen carrier polymerized human hemoglobin towards HepG2/C3A cells
N Chen, DA Belcher, C Savla, AF Palmer, F Berthiaume
Heliyon 9 (5), 2023
2023
Scalable Purification of Ultra-Pure Lumbricus terrestris Mega-Hemoglobin and Surface Modification using Bio-compatible Polymers for use as an Oxygen Therapeutic
C Savla
The Ohio State University, 2023
2023
Hemoglobin-based oxygen carriers and methods of making and using thereof
A Palmer, PJ Cabrales Arevalo, X Gu, C Savla
US Patent WO2022272124A1, 2022
2022
Scalable manufacturing platform for the production of PEGylated heme albumin
C Savla, AF Palmer
Biotechnology and bioengineering 119 (12), 3612-3622, 2022
2022
Bio-Compatible Polymer-Conjugated Extracellular Mega-Hemoglobin for Diverse Oxygen Therapeutic Applications
C Savla
2022 AIChE Annual Meeting, 2022
2022
Photocatalytic Synthesis of a Novel Polydopamine-Coated Acellular Mega-Hemoglobin As a Potential Oxygen Therapeutic
E Pozy, C Savla, A Palmer
2022 AIChE Annual Meeting, 2022
2022
Surface Camouflaged Lumbricus Terrestris mega-Hemoglobin for Diverse Oxygen Therapeutic Applications
C Savla, A Palmer
2021 AIChE Annual Meeting, 2021
2021
Diverse Oxygen Therapeutic Applications of Surface Camouflaged Extracellular Annelid Mega-Hemoglobin
C Savla, A Palmer
2020 Virtual AIChE Annual Meeting, 2020
2020
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