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Vaughn Smider
Vaughn Smider
President, Applied Biomedical Science Institute
Adresse e-mail validée de absinstitute.org - Page d'accueil
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Synthesis of site-specific antibody-drug conjugates using unnatural amino acids
JY Axup, KM Bajjuri, M Ritland, BM Hutchins, CH Kim, SA Kazane, ...
Proceedings of the National Academy of Sciences 109 (40), 16101-16106, 2012
7092012
Restoration of X-ray resistance and V (D) J recombination in mutant cells by Ku cDNA
V Smider, WK Rathmell, MR Lieber, G Chu
Science 266 (5183), 288-291, 1994
4201994
Reshaping antibody diversity
F Wang, DC Ekiert, I Ahmad, W Yu, Y Zhang, O Bazirgan, A Torkamani, ...
Cell 153 (6), 1379-1393, 2013
2202013
Ku86 defines the genetic defect and restores X-ray resistance and V (D) J recombination to complementation group 5 hamster cell mutants
A Errami, V Smider, WK Rathmell, DM He, EA Hendrickson, ...
Molecular and cellular biology, 1996
2101996
Synthesis of bispecific antibodies using genetically encoded unnatural amino acids
CH Kim, JY Axup, A Dubrovska, SA Kazane, BA Hutchins, ED Wold, ...
Journal of the American Chemical Society 134 (24), 9918-9921, 2012
2042012
Protein evolution with an expanded genetic code
CC Liu, AV Mack, ML Tsao, JH Mills, HS Lee, H Choe, M Farzan, ...
Proceedings of the National Academy of Sciences 105 (46), 17688-17693, 2008
1882008
Site-specific DNA-antibody conjugates for specific and sensitive immuno-PCR
SA Kazane, D Sok, EH Cho, ML Uson, P Kuhn, PG Schultz, VV Smider
Proceedings of the National Academy of Sciences 109 (10), 3731-3736, 2012
1832012
Rapid elicitation of broadly neutralizing antibodies to HIV by immunization in cows
D Sok, KM Le, M Vadnais, KL Saye-Francisco, JG Jardine, JL Torres, ...
Nature 548 (7665), 108-111, 2017
1672017
Antibody conjugates with unnatural amino acids
TJ Hallam, E Wold, A Wahl, VV Smider
Molecular pharmaceutics 12 (6), 1848-1862, 2015
1312015
Self-assembled antibody multimers through peptide nucleic acid conjugation
SA Kazane, JY Axup, CH Kim, M Ciobanu, ED Wold, S Barluenga, ...
Journal of the American Chemical Society 135 (1), 340-346, 2013
1052013
Site-specific coupling and sterically controlled formation of multimeric antibody fab fragments with unnatural amino acids
BM Hutchins, SA Kazane, K Staflin, JS Forsyth, B Felding-Habermann, ...
Journal of molecular biology 406 (4), 595-603, 2011
1002011
A structurally distinct human mycoplasma protein that generically blocks antigen-antibody union
RK Grover, X Zhu, T Nieusma, T Jones, I Boero, AS MacLeod, A Mark, ...
Science 343 (6171), 656-661, 2014
982014
The end-joining reaction in V (D) J recombination
V Smider, G Chu
Seminars in immunology 9 (3), 189-197, 1997
971997
A genetically encoded aza-Michael acceptor for covalent cross-linking of protein–receptor complexes
JL Furman, M Kang, S Choi, Y Cao, ED Wold, SB Sun, VV Smider, ...
Journal of the American Chemical Society 136 (23), 8411-8417, 2014
942014
Somatic hypermutation maintains antibody thermodynamic stability during affinity maturation
F Wang, S Sen, Y Zhang, I Ahmad, X Zhu, IA Wilson, VV Smider, ...
Proceedings of the National Academy of Sciences 110 (11), 4261-4266, 2013
942013
Bispecific small molecule–antibody conjugate targeting prostate cancer
CH Kim, JY Axup, BR Lawson, H Yun, V Tardif, SH Choi, Q Zhou, ...
Proceedings of the National Academy of Sciences 110 (44), 17796-17801, 2013
902013
Evolution of proteins with genetically encoded “chemical warheads”
CC Liu, AV Mack, EM Brustad, JH Mills, D Groff, VV Smider, PG Schultz
Journal of the American Chemical Society 131 (28), 9616-9617, 2009
892009
Mechanistic studies of the immunochemical termination of self-tolerance with unnatural amino acids
J Grünewald, GS Hunt, L Dong, F Niessen, BG Wen, ML Tsao, R Perera, ...
Proceedings of the National Academy of Sciences 106 (11), 4337-4342, 2009
762009
Immunochemical termination of self-tolerance
J Grünewald, ML Tsao, R Perera, L Dong, F Niessen, BG Wen, DM Kubitz, ...
Proceedings of the National Academy of Sciences 105 (32), 11276-11280, 2008
762008
Structural and genetic diversity in antibody repertoires from diverse species
M de Los Rios, MF Criscitiello, VV Smider
Current opinion in structural biology 33, 27-41, 2015
752015
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