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Hervé MINOUX
Hervé MINOUX
Verified email at sanofi.com
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Cited by
Year
Cytoplasmic STAT3 represses autophagy by inhibiting PKR activity
S Shen, M Niso-Santano, S Adjemian, T Takehara, SA Malik, H Minoux, ...
Molecular cell 48 (5), 667-680, 2012
2762012
Cation− π interactions in proteins: can simple models provide an accurate description?
H Minoux, C Chipot
Journal of the American Chemical Society 121 (44), 10366-10372, 1999
2421999
Association and dissociation of autophagy, apoptosis and necrosis by systematic chemical study
S Shen, O Kepp, M Michaud, I Martins, H Minoux, D Metivier, MC Maiuri, ...
Oncogene 30 (45), 4544-4556, 2011
1892011
An electrostatic basis for the stability of thermophilic proteins
BN Dominy, H Minoux, CL Brooks III
Proteins: Structure, Function, and Bioinformatics 57 (1), 128-141, 2004
1682004
Machine learning force fields and coarse-grained variables in molecular dynamics: application to materials and biological systems
P Gkeka, G Stoltz, A Barati Farimani, Z Belkacemi, M Ceriotti, JD Chodera, ...
Journal of chemical theory and computation 16 (8), 4757-4775, 2020
1632020
Organophosphorus derivatives of indazoles and use thereof as medicinal products
MP Cherrier, F Clerc, A Commercon, P Mailliet, H Minoux, ...
US Patent 7,491,710, 2009
992009
Scaffold-constrained molecular generation
M Langevin, H Minoux, M Levesque, M Bianciotto
Journal of Chemical Information and Modeling 60 (12), 5637-5646, 2020
532020
Tricyclic Series of Heat Shock Protein 90 (Hsp90) Inhibitors Part I: Discovery of Tricyclic Imidazo[4,5-c]pyridines as Potent Inhibitors of the Hsp90 Molecular …
F Vallée, C Carrez, F Pilorge, A Dupuy, A Parent, L Bertin, F Thompson, ...
Journal of medicinal chemistry 54 (20), 7206-7219, 2011
522011
Differential water thermodynamics determine PI3K-beta/delta selectivity for solvent-exposed ligand modifications
D Robinson, T Bertrand, JC Carry, F Halley, A Karlsson, M Mathieu, ...
Journal of Chemical Information and Modeling 56 (5), 886-894, 2016
442016
SAR156497, an exquisitely selective inhibitor of aurora kinases
JC Carry, F Clerc, H Minoux, L Schio, J Mauger, A Nair, E Parmantier, ...
Journal of medicinal chemistry 58 (1), 362-375, 2015
392015
Fluorene derivatives, composition containing said derivatives and the use thereof
P Mailliet, L Bertin, F Thompson, JM Ruxer, F Pilorge, D Benard, ...
US Patent 7,674,795, 2010
362010
Structural analysis of the KGD sequence loop of barbourin, an αIIbβ3-specific disintegrin
H Minoux, C Chipot, D Brown, B Maigret
Journal of Computer-Aided Molecular Design 14, 317-327, 2000
272000
Synthesis of carbohydrate-based peptidomimetics as potential selective fibrinogen receptor antagonists
N Moitessier, H Minoux, B Maigret, F Chrétien, Y Chapleu
Letters in Peptide Science 5, 75-78, 1998
271998
Hydrazinocarbonyl-thieno [2, 3-C] pyrazoles, process for preparing them, compositions containing them and use thereof
C Barberis, JC Carry, G Doerflinger, D Barbalat-damour, F Clerc, ...
US Patent 7,595,320, 2009
222009
Substituted thieno [2, 3-c] pyrazoles and their use as medicinal products
A Bigot, F Clerc, G Doerflinger, S Mignani, H Minoux
US Patent App. 10/900,549, 2005
192005
Tirofiban blocks platelet adhesion to fibrin with minimal perturbation of GpIIb/IIIa structure
RR Hantgan, MC Stahle, GW Jerome, C Nagaswami, JW Weisel
Thrombosis and haemostasis 87 (05), 910-917, 2002
192002
Contact map fingerprints of protein–ligand unbinding trajectories reveal mechanisms determining residence times computed from scaled molecular dynamics
M Bianciotto, P Gkeka, DB Kokh, RC Wade, H Minoux
Journal of Chemical Theory and Computation 17 (10), 6522-6535, 2021
152021
Elucidation of a common structure of selective fibrinogen receptor antagonists
H Minoux, N Moitessier, Y Chapleur, B Maigret
Journal of computer-aided molecular design 12, 533-542, 1998
121998
Pyrazolylbenzimidazole derivatives, compositions containing them and use thereof
MP Cherrier, E Parmantier, H Minoux, F Clerc, O Angouillant-Boniface, ...
US Patent 9,126,969, 2015
102015
HSP90 inhibitory carbazole derivatives, compositions containing same and use thereof
JM Ruxer, V Certal, M Alasia, L Bertin, H Minoux, P Mailliet, F Halley, ...
US Patent 8,309,721, 2012
102012
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