SARS-CoV-2 receptor ACE2 is an interferon-stimulated gene in human airway epithelial cells and is detected in specific cell subsets across tissues CGK Ziegler, SJ Allon, SK Nyquist, IM Mbano, VN Miao, CN Tzouanas, ... Cell, 2020 | 2352 | 2020 |
Mechanism of the Nrf2/Keap1/ARE signaling system VO Tkachev, EB Menshchikova, NK Zenkov Biochemistry (Moscow) 76 (4), 407-422, 2011 | 285 | 2011 |
Innovations present in the primate interneuron repertoire FM Krienen, M Goldman, Q Zhang, RCH Del Rosario, M Florio, ... Nature 586 (7828), 262-269, 2020 | 232 | 2020 |
Chimeric antigen receptor T cell–mediated neurotoxicity in nonhuman primates A Taraseviciute, V Tkachev, R Ponce, CJ Turtle, JM Snyder, HD Liggitt, ... Cancer discovery 8 (6), 750-763, 2018 | 219 | 2018 |
The IL-33/ST2 axis augments effector T-cell responses during acute GVHD DK Reichenbach, V Schwarze, BM Matta, V Tkachev, E Lieberknecht, ... Blood, The Journal of the American Society of Hematology 125 (20), 3183-3192, 2015 | 176 | 2015 |
Effector T cells require fatty acid metabolism during murine graft-versus-host disease CA Byersdorfer, V Tkachev, AW Opipari, S Goodell, J Swanson, ... Blood 122 (18), 3230-3237, 2013 | 160 | 2013 |
Phase II trial of costimulation blockade with abatacept for prevention of acute GVHD B Watkins, M Qayed, C McCracken, B Bratrude, K Betz, Y Suessmuth, ... Journal of Clinical Oncology 39 (17), 1865-1877, 2021 | 135 | 2021 |
Programmed death-1 controls T cell survival by regulating oxidative metabolism V Tkachev, S Goodell, AW Opipari, LY Hao, L Franchi, GD Glick, ... The Journal of Immunology 194 (12), 5789-5800, 2015 | 128 | 2015 |
Keap1/Nrf2/ARE redox-sensitive signaling system as a pharmacological target NK Zenkov, EB Menshchikova, VO Tkachev Biochemistry (Moscow) 78 (1), 19-36, 2013 | 105 | 2013 |
Current concepts and advances in graft-versus-host disease immunology GR Hill, BC Betts, V Tkachev, LS Kean, BR Blazar Annual review of immunology 39, 19-49, 2021 | 99 | 2021 |
Programmed death ligand-1 expression on donor T cells drives graft-versus-host disease lethality A Saha, RS O’connor, G Thangavelu, SB Lovitch, DB Dandamudi, ... The Journal of clinical investigation 126 (7), 2642-2660, 2016 | 95 | 2016 |
Anaplerotic metabolism of alloreactive T cells provides a metabolic approach to treat graft-versus-host disease GD Glick, R Rossignol, CA Lyssiotis, D Wahl, C Lesch, B Sanchez, X Liu, ... Journal of Pharmacology and Experimental Therapeutics 351 (2), 298-307, 2014 | 73 | 2014 |
Combined OX40L and mTOR blockade controls effector T cell activation while preserving Treg reconstitution after transplant V Tkachev, SN Furlan, B Watkins, DJ Hunt, HB Zheng, ... Science translational medicine 9 (408), 2017 | 71 | 2017 |
Transcriptome analysis of GVHD reveals aurora kinase A as a targetable pathway for disease prevention SN Furlan, B Watkins, V Tkachev, R Flynn, S Cooley, S Ramakrishnan, ... Science translational medicine 7 (315), 315ra191-315ra191, 2015 | 62 | 2015 |
Spatiotemporal single-cell profiling reveals that invasive and tissue-resident memory donor CD8+ T cells drive gastrointestinal acute graft-versus-host disease V Tkachev, J Kaminski, EL Potter, SN Furlan, A Yu, DJ Hunt, C McGuckin, ... Science Translational Medicine 13 (576), 2021 | 47 | 2021 |
CD28 blockade controls T cell activation to prevent graft-versus-host disease in primates. BK Watkins, V Tkachev, SN Furlan, DJ Hunt, K Betz, A Yu, M Brown, ... The Journal of clinical investigation 128 (9), 3991-4007, 2018 | 47 | 2018 |
Systems analysis uncovers inflammatory Th/Tc17-driven modules during acute GVHD in monkey and human T cells SN Furlan, B Watkins, V Tkachev, S Cooley, A Panoskaltsis-Mortari, ... Blood, The Journal of the American Society of Hematology 128 (21), 2568-2579, 2016 | 46 | 2016 |
Innovations in primate interneuron repertoire FM Krienen, M Goldman, Q Zhang, R del Rosario, M Florio, R Machold, ... bioRxiv, 709501, 2019 | 34 | 2019 |
IL-2 enhances ex vivo–expanded regulatory T-cell persistence after adoptive transfer SN Furlan, K Singh, C Lopez, V Tkachev, DJ Hunt, J Hibbard, KM Betz, ... Blood Advances 4 (8), 1594-1605, 2020 | 31 | 2020 |
The knife's edge of tolerance: inducing stable multilineage mixed chimerism but with a significant risk of CMV reactivation and disease in Rhesus macaques HB Zheng, B Watkins, V Tkachev, S Yu, D Tran, S Furlan, K Zeleski, ... American Journal of Transplantation 17 (3), 657-670, 2017 | 29 | 2017 |