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Victor Tkachev
Victor Tkachev
Boston Children's Hospital/Harvard Medical School
Verified email at childrens.harvard.edu
Title
Cited by
Cited by
Year
SARS-CoV-2 receptor ACE2 is an interferon-stimulated gene in human airway epithelial cells and is detected in specific cell subsets across tissues
CGK Ziegler, SJ Allon, SK Nyquist, IM Mbano, VN Miao, CN Tzouanas, ...
Cell, 2020
23522020
Mechanism of the Nrf2/Keap1/ARE signaling system
VO Tkachev, EB Menshchikova, NK Zenkov
Biochemistry (Moscow) 76 (4), 407-422, 2011
2852011
Innovations present in the primate interneuron repertoire
FM Krienen, M Goldman, Q Zhang, RCH Del Rosario, M Florio, ...
Nature 586 (7828), 262-269, 2020
2322020
Chimeric antigen receptor T cell–mediated neurotoxicity in nonhuman primates
A Taraseviciute, V Tkachev, R Ponce, CJ Turtle, JM Snyder, HD Liggitt, ...
Cancer discovery 8 (6), 750-763, 2018
2192018
The IL-33/ST2 axis augments effector T-cell responses during acute GVHD
DK Reichenbach, V Schwarze, BM Matta, V Tkachev, E Lieberknecht, ...
Blood, The Journal of the American Society of Hematology 125 (20), 3183-3192, 2015
1762015
Effector T cells require fatty acid metabolism during murine graft-versus-host disease
CA Byersdorfer, V Tkachev, AW Opipari, S Goodell, J Swanson, ...
Blood 122 (18), 3230-3237, 2013
1602013
Phase II trial of costimulation blockade with abatacept for prevention of acute GVHD
B Watkins, M Qayed, C McCracken, B Bratrude, K Betz, Y Suessmuth, ...
Journal of Clinical Oncology 39 (17), 1865-1877, 2021
1352021
Programmed death-1 controls T cell survival by regulating oxidative metabolism
V Tkachev, S Goodell, AW Opipari, LY Hao, L Franchi, GD Glick, ...
The Journal of Immunology 194 (12), 5789-5800, 2015
1282015
Keap1/Nrf2/ARE redox-sensitive signaling system as a pharmacological target
NK Zenkov, EB Menshchikova, VO Tkachev
Biochemistry (Moscow) 78 (1), 19-36, 2013
1052013
Current concepts and advances in graft-versus-host disease immunology
GR Hill, BC Betts, V Tkachev, LS Kean, BR Blazar
Annual review of immunology 39, 19-49, 2021
992021
Programmed death ligand-1 expression on donor T cells drives graft-versus-host disease lethality
A Saha, RS O’connor, G Thangavelu, SB Lovitch, DB Dandamudi, ...
The Journal of clinical investigation 126 (7), 2642-2660, 2016
952016
Anaplerotic metabolism of alloreactive T cells provides a metabolic approach to treat graft-versus-host disease
GD Glick, R Rossignol, CA Lyssiotis, D Wahl, C Lesch, B Sanchez, X Liu, ...
Journal of Pharmacology and Experimental Therapeutics 351 (2), 298-307, 2014
732014
Combined OX40L and mTOR blockade controls effector T cell activation while preserving Treg reconstitution after transplant
V Tkachev, SN Furlan, B Watkins, DJ Hunt, HB Zheng, ...
Science translational medicine 9 (408), 2017
712017
Transcriptome analysis of GVHD reveals aurora kinase A as a targetable pathway for disease prevention
SN Furlan, B Watkins, V Tkachev, R Flynn, S Cooley, S Ramakrishnan, ...
Science translational medicine 7 (315), 315ra191-315ra191, 2015
622015
Spatiotemporal single-cell profiling reveals that invasive and tissue-resident memory donor CD8+ T cells drive gastrointestinal acute graft-versus-host disease
V Tkachev, J Kaminski, EL Potter, SN Furlan, A Yu, DJ Hunt, C McGuckin, ...
Science Translational Medicine 13 (576), 2021
472021
CD28 blockade controls T cell activation to prevent graft-versus-host disease in primates.
BK Watkins, V Tkachev, SN Furlan, DJ Hunt, K Betz, A Yu, M Brown, ...
The Journal of clinical investigation 128 (9), 3991-4007, 2018
472018
Systems analysis uncovers inflammatory Th/Tc17-driven modules during acute GVHD in monkey and human T cells
SN Furlan, B Watkins, V Tkachev, S Cooley, A Panoskaltsis-Mortari, ...
Blood, The Journal of the American Society of Hematology 128 (21), 2568-2579, 2016
462016
Innovations in primate interneuron repertoire
FM Krienen, M Goldman, Q Zhang, R del Rosario, M Florio, R Machold, ...
bioRxiv, 709501, 2019
342019
IL-2 enhances ex vivo–expanded regulatory T-cell persistence after adoptive transfer
SN Furlan, K Singh, C Lopez, V Tkachev, DJ Hunt, J Hibbard, KM Betz, ...
Blood Advances 4 (8), 1594-1605, 2020
312020
The knife's edge of tolerance: inducing stable multilineage mixed chimerism but with a significant risk of CMV reactivation and disease in Rhesus macaques
HB Zheng, B Watkins, V Tkachev, S Yu, D Tran, S Furlan, K Zeleski, ...
American Journal of Transplantation 17 (3), 657-670, 2017
292017
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