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Howard McLeod
Howard McLeod
Utah Tech University
Adresse e-mail validée de utahtech.edu - Page d'accueil
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Pharmacogenomics—drug disposition, drug targets, and side effects
WE Evans, HL McLeod
New England journal of medicine 348 (6), 538-549, 2003
25112003
Doxorubicin pathways: pharmacodynamics and adverse effects
CF Thorn, C Oshiro, S Marsh, T Hernandez-Boussard, H McLeod, ...
Pharmacogenetics and genomics 21 (7), 440-446, 2011
19992011
Effect of VKORC1 haplotypes on transcriptional regulation and warfarin dose
MJ Rieder, AP Reiner, BF Gage, DA Nickerson, CS Eby, HL McLeod, ...
New England Journal of Medicine 352 (22), 2285-2293, 2005
18402005
Use of pharmacogenetic and clinical factors to predict the therapeutic dose of warfarin
BF Gage, C Eby, JA Johnson, E Deych, MJ Rieder, PM Ridker, ...
Clinical Pharmacology & Therapeutics 84 (3), 326-331, 2008
9992008
Genomics and drug response
L Wang, HL McLeod, RM Weinshilboum
New England Journal of Medicine 364 (12), 1144-1153, 2011
7622011
Platinum neurotoxicity pharmacogenetics
SR McWhinney, RM Goldberg, HL McLeod
Molecular cancer therapeutics 8 (1), 10-16, 2009
7112009
Mechanism-based inhibition of cytochrome P450 3A4 by therapeutic drugs
S Zhou, SY Chan, BC Goh, E Chan, W Duan, M Huang, HL McLeod
Clinical pharmacokinetics 44, 279-304, 2005
6102005
MDR1 pharmacogenetics: frequency of the C3435T mutation in exon 26 is significantly influenced by ethnicity
MM Ameyaw, F Regateiro, T Li, X Liu, M Tariq, A Mobarek, N Thornton, ...
Pharmacogenetics and Genomics 11 (3), 217-221, 2001
6082001
Clinical Pharmacogenetics Implementation Consortium (CPIC) guideline for dihydropyrimidine dehydrogenase genotype and fluoropyrimidine dosing: 2017 update
U Amstutz, LM Henricks, SM Offer, J Barbarino, JHM Schellens, JJ Swen, ...
Clinical Pharmacology & Therapeutics 103 (2), 210-216, 2018
5792018
UGT1A1* 28 genotype and irinotecan-induced neutropenia: dose matters
JM Hoskins, RM Goldberg, P Qu, JG Ibrahim, HL McLeod
Journal of the National Cancer Institute 99 (17), 1290-1295, 2007
5782007
Gene expression profiles and molecular markers to predict recurrence of Dukes' B colon cancer
Y Wang, T Jatkoe, Y Zhang, MG Mutch, D Talantov, J Jiang, HL McLeod, ...
Journal of clinical oncology 22 (9), 1564-1571, 2004
5762004
PI3K/Akt/mTOR pathway as a target for cancer therapy
D Morgensztern, HL McLeod
Anti-cancer drugs 16 (8), 797-803, 2005
5672005
Genetic polymorphism of thiopurine methyltransferase and its clinical relevance for childhood acute lymphoblastic leukemia
HL McLeod, EY Krynetski, MV Relling, WE Evans
Leukemia 14 (4), 567-572, 2000
5642000
Carbamazepine, HLA-B*1502 and Risk of Stevens–Johnson Syndrome and Toxic Epidermal Necrolysis: US FDA Recommendations
PB Ferrell, HL McLeod
Pharmacogenomics 9 (10), 1543-1546, 2008
5012008
Induction of thymidylate synthase as a 5-fluorouracil resistance mechanism
GJ Peters, HHJ Backus, S Freemantle, B Van Triest, G Codacci-Pisanelli, ...
Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1587 (2-3 …, 2002
5002002
Thiopurine methyltransferase genotype predicts therapy-limiting severe toxicity from azathioprine
AJ Black, HL McLeod, HA Capell, RH Powrie, LK Matowe, SC Pritchard, ...
Annals of internal medicine 129 (9), 716-718, 1998
4891998
Strategies for enzyme/prodrug cancer therapy
G Xu, HL McLeod
Clinical Cancer Research 7 (11), 3314-3324, 2001
4802001
Molecular basis of the human dihydropyrimidine dehydrogenase deficiency and 5-fluorouracil toxicity.
X Wei, HL McLeod, J McMurrough, FJ Gonzalez, P Fernandez-Salguero
The Journal of clinical investigation 98 (3), 610-615, 1996
4751996
The Clinical Pharmacogenetics Implementation Consortium Guideline for SLCO1B1 and Simvastatin‐Induced Myopathy: 2014 Update
LB Ramsey, SG Johnson, KE Caudle, CE Haidar, D Voora, RA Wilke, ...
Clinical Pharmacology & Therapeutics 96 (4), 423-428, 2014
4662014
A genome-based model for adjusting radiotherapy dose (GARD): a retrospective, cohort-based study
JG Scott, A Berglund, MJ Schell, I Mihaylov, WJ Fulp, B Yue, E Welsh, ...
The lancet oncology 18 (2), 202-211, 2017
4612017
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