Progression of osteosarcoma from a non-metastatic to a metastatic phenotype is causally associated with activation of an autocrine and paracrine uPA axis L Endo-Munoz, N Cai, A Cumming, R Macklin, L Merida de Long, ... PLoS One 10 (8), e0133592, 2015 | 61 | 2015 |
Extracellular vesicles secreted by highly metastatic clonal variants of osteosarcoma preferentially localize to the lungs and induce metastatic behaviour in poorly metastatic … R Macklin, H Wang, D Loo, S Martin, A Cumming, N Cai, R Lane, ... Oncotarget 7 (28), 43570, 2016 | 46 | 2016 |
Auranofin is a potent suppressor of osteosarcoma metastasis E Topkas, N Cai, A Cumming, M Hazar-Rethinam, OM Gannon, ... Oncotarget 7 (1), 831, 2016 | 44 | 2016 |
Mass spectrometric analysis of TRPM6 and TRPM7 phosphorylation reveals regulatory mechanisms of the channel-kinases N Cai, Z Bai, V Nanda, LW Runnels Scientific reports 7 (1), 42739, 2017 | 35 | 2017 |
CNNM proteins selectively bind to the TRPM7 channel to stimulate divalent cation entry into cells Z Bai, J Feng, GAC Franken, N Al’Saadi, N Cai, AS Yu, L Lou, Y Komiya, ... PLoS biology 19 (12), e3001496, 2021 | 29 | 2021 |
The kinase activity of the channel-kinase protein TRPM7 regulates stability and localization of the TRPM7 channel in polarized epithelial cells N Cai, L Lou, N Al-Saadi, S Tetteh, LW Runnels Journal of Biological Chemistry 293 (29), 11491-11504, 2018 | 19 | 2018 |
Merida de Long L., Topkas E., Mukhopadhyay P., Hill M., Saunders NA Progression of osteosarcoma from a non-metastatic to a metastatic phenotype is causally associated with … L Endo-Munoz, N Cai, A Cumming, R Macklin PLoS One 10 (8), 2015 | 13 | 2015 |
Hepatocystin is essential for TRPM7 function during early embryogenesis JD Overton, Y Komiya, C Mezzacappa, K Nama, N Cai, L Lou, SV Fedeles, ... Scientific reports 5 (1), 18395, 2015 | 10 | 2015 |
A nonredundant role for the TRPM6 channel in neural tube closure Y Komiya, Z Bai, N Cai, L Lou, N Al-Saadi, C Mezzacappa, R Habas, ... Scientific reports 7 (1), 15623, 2017 | 9 | 2017 |
257: TXNRD2 and DCBLD2 are novel targets of osteosarcoma metastasis E Topkas, N Cai, A Cumming, N Saunders, L Endo-Munoz European Journal of Cancer, S60, 2014 | 4 | 2014 |
CNNM PROTEINS REGULATE THE TRPM7 CHANNEL TO CONTROL CELLULAR DIVALENT CATION ENTRY Z Bai, J Feng, GAC Franken, N Al’Saadi, N Cai, AS Yu, L Lou, Y Komiya, ... On the Origin and Function of Renal Magnesium Transport 19, 101, 2021 | | 2021 |
The functional interplay between TPRM7 channel-kinase autophosphorylation and its cellular regulation N Cai Rutgers University-School of Graduate Studies, 2018 | | 2018 |
The Channel-Kinase TRPM7 is Regulated by the Small Signaling Protein 14-3-3 theta N Cai, LW Runnels MOLECULAR BIOLOGY OF THE CELL 26, 2015 | | 2015 |
Identification and validation of two novel metastatic markers in Osteosarcoma E Topkas, N Cai, A Cumming, NA Saunders, L Endo-Munoz Clinical and Experimental Metastasis 32 (3), 242-243, 2015 | | 2015 |
An inhibitor of uPA reduces osteosarcoma metastasis by blocking signaling in tumour cells and the bone marrow microenvironment. LB Endo-Munoz, N Cai, A Cumming, D Loo, M Hill, P Mukhopadhyay, ... Cancer Research 73 (8_Supplement), 3948-3948, 2013 | | 2013 |